Subtotal Resection of an Anaplastic Ganglioglioma in Pregnancy
Background. Anaplastic ganglioglioma is a rare malignant brain tumor associated with high morbidity and mortality. The diagnosis of a central nervous system malignancy in the early 3rd trimester presents management challenges to both neurosurgeons and obstetricians. Case. A 33-year-old woman, gravid...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Obstetrics and Gynecology |
| Online Access: | http://dx.doi.org/10.1155/2018/4606354 |
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| author | Matthew J. Bicocca Andrea R. Gilbert Saeed S. Sadrameli Michael L. Pirics |
| author_facet | Matthew J. Bicocca Andrea R. Gilbert Saeed S. Sadrameli Michael L. Pirics |
| author_sort | Matthew J. Bicocca |
| collection | DOAJ |
| description | Background. Anaplastic ganglioglioma is a rare malignant brain tumor associated with high morbidity and mortality. The diagnosis of a central nervous system malignancy in the early 3rd trimester presents management challenges to both neurosurgeons and obstetricians. Case. A 33-year-old woman, gravida 2 para 1, presented at 28 6/7 weeks with four months of worsening headaches, nausea, vomiting, and mental status changes due to a 7.5 cm anaplastic ganglioglioma. Maternal deterioration necessitated subtotal tumor debulking allowing prolongation of the gestation to 34 6/7 weeks. After delivery, the patient underwent further resection, followed by chemotherapy and radiation. Both mother and infant are well. Discussion. This case underscores the importance of timely diagnostic imaging in pregnant women and demonstrates subtotal tumor debulking as a viable means of prolonging gestation. |
| format | Article |
| id | doaj-art-83df00e2b23f4059a65892b3f9b9d9bc |
| institution | Kabale University |
| issn | 2090-6684 2090-6692 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Obstetrics and Gynecology |
| spelling | doaj-art-83df00e2b23f4059a65892b3f9b9d9bc2025-08-20T03:37:37ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922018-01-01201810.1155/2018/46063544606354Subtotal Resection of an Anaplastic Ganglioglioma in PregnancyMatthew J. Bicocca0Andrea R. Gilbert1Saeed S. Sadrameli2Michael L. Pirics3Department of Obstetrics and Gynecology, Houston Methodist Hospital, Houston, TX, USADepartment of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX, USADepartment of Neurosurgery, Houston Methodist Hospital, Houston, TX, USADepartment of Obstetrics and Gynecology, Houston Methodist Hospital, Houston, TX, USABackground. Anaplastic ganglioglioma is a rare malignant brain tumor associated with high morbidity and mortality. The diagnosis of a central nervous system malignancy in the early 3rd trimester presents management challenges to both neurosurgeons and obstetricians. Case. A 33-year-old woman, gravida 2 para 1, presented at 28 6/7 weeks with four months of worsening headaches, nausea, vomiting, and mental status changes due to a 7.5 cm anaplastic ganglioglioma. Maternal deterioration necessitated subtotal tumor debulking allowing prolongation of the gestation to 34 6/7 weeks. After delivery, the patient underwent further resection, followed by chemotherapy and radiation. Both mother and infant are well. Discussion. This case underscores the importance of timely diagnostic imaging in pregnant women and demonstrates subtotal tumor debulking as a viable means of prolonging gestation.http://dx.doi.org/10.1155/2018/4606354 |
| spellingShingle | Matthew J. Bicocca Andrea R. Gilbert Saeed S. Sadrameli Michael L. Pirics Subtotal Resection of an Anaplastic Ganglioglioma in Pregnancy Case Reports in Obstetrics and Gynecology |
| title | Subtotal Resection of an Anaplastic Ganglioglioma in Pregnancy |
| title_full | Subtotal Resection of an Anaplastic Ganglioglioma in Pregnancy |
| title_fullStr | Subtotal Resection of an Anaplastic Ganglioglioma in Pregnancy |
| title_full_unstemmed | Subtotal Resection of an Anaplastic Ganglioglioma in Pregnancy |
| title_short | Subtotal Resection of an Anaplastic Ganglioglioma in Pregnancy |
| title_sort | subtotal resection of an anaplastic ganglioglioma in pregnancy |
| url | http://dx.doi.org/10.1155/2018/4606354 |
| work_keys_str_mv | AT matthewjbicocca subtotalresectionofananaplasticgangliogliomainpregnancy AT andreargilbert subtotalresectionofananaplasticgangliogliomainpregnancy AT saeedssadrameli subtotalresectionofananaplasticgangliogliomainpregnancy AT michaellpirics subtotalresectionofananaplasticgangliogliomainpregnancy |