Incompletely closed HIV-1CH040 envelope glycoproteins resist broadly neutralizing antibodies while mediating efficient HIV-1 entry

Incompletely closed HIV-1CH040 envelope glycoproteins resist broadly neutralizing antibodies while mediating efficient HIV-1 entry

Abstract HIV-1 envelope glycoproteins (Envs) mediate viral entry and are sole target of neutralizing antibodies. Thus, HIV-1 Envs must maintain a delicate balance between evading neutralizing antibodies while still preserving viral compatibility to mediate entry into target cells. Here, we studied t...

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Bibliographic Details
Main Authors: Durgadevi Parthasarathy, Stephanie Pickthorn, Shamim Ahmed, Dmitry Mazurov, Jeffy Jeffy, Rajni Kant Shukla, Amit Sharma, Alon Herschhorn
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:npj Viruses
Online Access:https://doi.org/10.1038/s44298-024-00082-w
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