A Rare Complication following Thyroid Percutaneous Ethanol Injection: Plummer Adenoma
Percutaneous ethanol injection (PEI) is a technique used only for benign thyroid nodules, cystic or mixed cystic-solid with a large fluid component. It is a quite low-cost, safe, and outpatient method of treatment. Rare and severe complications have been described after PEI: jugular vein thrombosis...
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Wiley
2017-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2017/1026139 |
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| author | Roberto Cesareo Anda Mihaela Naciu Valerio Pasqualini Giuseppe Pelle Silvia Manfrini Gaia Tabacco Angelo Lauria Pantano Alessandro Casini Roberto Cianni Andrea Palermo |
| author_facet | Roberto Cesareo Anda Mihaela Naciu Valerio Pasqualini Giuseppe Pelle Silvia Manfrini Gaia Tabacco Angelo Lauria Pantano Alessandro Casini Roberto Cianni Andrea Palermo |
| author_sort | Roberto Cesareo |
| collection | DOAJ |
| description | Percutaneous ethanol injection (PEI) is a technique used only for benign thyroid nodules, cystic or mixed cystic-solid with a large fluid component. It is a quite low-cost, safe, and outpatient method of treatment. Rare and severe complications have been described after PEI: jugular vein thrombosis and severe ethanol toxic necrosis of the larynx combined with necrotic dermatitis. Moreover, only four thyrotoxicosis cases due to Graves’ disease have been reported. We report a case of 58-year-old female with a voluminous thyroid cystic nodule, occupying almost the entire left thyroid lobe. Our patient had already performed surgical visit and intervention of thyroidectomy had been proposed to her, which she refused. At baseline, our patient has a normal thyroid function with negative autoantibodies. According to the nodular structure, intervention of PEI has been performed with a significant improvement of compressive symptoms and cosmetic disorders. About 30 days after treatment, there was a significant volume reduction, but patient developed an acclaimed symptomatic thyrotoxicosis. After ruling out several causes of hyperthyroidism and according to the thyroid scintigraphy findings, we made the diagnosis of Plummer adenoma. To our knowledge, our patient is the first case of Plummer adenoma following PEI treatment of nontoxic thyroid nodule. |
| format | Article |
| id | doaj-art-83d9e124256a4c61947f038f1bb5ed46 |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-83d9e124256a4c61947f038f1bb5ed462025-08-20T03:37:37ZengWileyCase Reports in Endocrinology2090-65012090-651X2017-01-01201710.1155/2017/10261391026139A Rare Complication following Thyroid Percutaneous Ethanol Injection: Plummer AdenomaRoberto Cesareo0Anda Mihaela Naciu1Valerio Pasqualini2Giuseppe Pelle3Silvia Manfrini4Gaia Tabacco5Angelo Lauria Pantano6Alessandro Casini7Roberto Cianni8Andrea Palermo9Department of Internal Medicine, “S. M. Goretti” Hospital, Latina, ItalyDepartment of Endocrinology, University Campus Bio-Medico, Rome, ItalyDepartment of Radiology, “S. M. Goretti” Hospital, Latina, ItalyDepartment of Radiology, “S. M. Goretti” Hospital, Latina, ItalyDepartment of Endocrinology, University Campus Bio-Medico, Rome, ItalyDepartment of Endocrinology, University Campus Bio-Medico, Rome, ItalyDepartment of Endocrinology, University Campus Bio-Medico, Rome, ItalyDepartment of Internal Medicine, “S. M. Goretti” Hospital, Latina, ItalyDepartment of Radiology, “S. M. Goretti” Hospital, Latina, ItalyDepartment of Endocrinology, University Campus Bio-Medico, Rome, ItalyPercutaneous ethanol injection (PEI) is a technique used only for benign thyroid nodules, cystic or mixed cystic-solid with a large fluid component. It is a quite low-cost, safe, and outpatient method of treatment. Rare and severe complications have been described after PEI: jugular vein thrombosis and severe ethanol toxic necrosis of the larynx combined with necrotic dermatitis. Moreover, only four thyrotoxicosis cases due to Graves’ disease have been reported. We report a case of 58-year-old female with a voluminous thyroid cystic nodule, occupying almost the entire left thyroid lobe. Our patient had already performed surgical visit and intervention of thyroidectomy had been proposed to her, which she refused. At baseline, our patient has a normal thyroid function with negative autoantibodies. According to the nodular structure, intervention of PEI has been performed with a significant improvement of compressive symptoms and cosmetic disorders. About 30 days after treatment, there was a significant volume reduction, but patient developed an acclaimed symptomatic thyrotoxicosis. After ruling out several causes of hyperthyroidism and according to the thyroid scintigraphy findings, we made the diagnosis of Plummer adenoma. To our knowledge, our patient is the first case of Plummer adenoma following PEI treatment of nontoxic thyroid nodule.http://dx.doi.org/10.1155/2017/1026139 |
| spellingShingle | Roberto Cesareo Anda Mihaela Naciu Valerio Pasqualini Giuseppe Pelle Silvia Manfrini Gaia Tabacco Angelo Lauria Pantano Alessandro Casini Roberto Cianni Andrea Palermo A Rare Complication following Thyroid Percutaneous Ethanol Injection: Plummer Adenoma Case Reports in Endocrinology |
| title | A Rare Complication following Thyroid Percutaneous Ethanol Injection: Plummer Adenoma |
| title_full | A Rare Complication following Thyroid Percutaneous Ethanol Injection: Plummer Adenoma |
| title_fullStr | A Rare Complication following Thyroid Percutaneous Ethanol Injection: Plummer Adenoma |
| title_full_unstemmed | A Rare Complication following Thyroid Percutaneous Ethanol Injection: Plummer Adenoma |
| title_short | A Rare Complication following Thyroid Percutaneous Ethanol Injection: Plummer Adenoma |
| title_sort | rare complication following thyroid percutaneous ethanol injection plummer adenoma |
| url | http://dx.doi.org/10.1155/2017/1026139 |
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