Severe Human Intestinal Spirochetosis: An Unusual Cause of Diffuse Colonic Ulcerations in a Patient Living with HIV
We describe a case of a homosexual male with human immunodeficiency virus (HIV) and CD4 count of 246 presenting with acute severe bloody diarrhea. Infectious work up was negative, and colonoscopy revealed severe diffuse colonic ulcerations. Histopathologic analysis and Treponemal pallidum immunostai...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | Case Reports in Gastrointestinal Medicine |
| Online Access: | http://dx.doi.org/10.1155/2019/1504079 |
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| author | T. A. Ajose J. Aniekwena V. S. Effoe M. Simien |
| author_facet | T. A. Ajose J. Aniekwena V. S. Effoe M. Simien |
| author_sort | T. A. Ajose |
| collection | DOAJ |
| description | We describe a case of a homosexual male with human immunodeficiency virus (HIV) and CD4 count of 246 presenting with acute severe bloody diarrhea. Infectious work up was negative, and colonoscopy revealed severe diffuse colonic ulcerations. Histopathologic analysis and Treponemal pallidum immunostaining confirmed the diagnosis of intestinal spirochetosis. There was no evidence of co-infection with other pathogens. His symptoms completely resolved after a 14-day course of metronidazole. This case is notable as colonic ulceration of any severity in patients living with HIV is rarely identified with intestinal spirochetosis. Hence, it should be considered in the differential diagnosis of colonic ulcerations. |
| format | Article |
| id | doaj-art-83d5e3426b6a437295e986433c78be78 |
| institution | Kabale University |
| issn | 2090-6528 2090-6536 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Gastrointestinal Medicine |
| spelling | doaj-art-83d5e3426b6a437295e986433c78be782025-02-03T05:52:19ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362019-01-01201910.1155/2019/15040791504079Severe Human Intestinal Spirochetosis: An Unusual Cause of Diffuse Colonic Ulcerations in a Patient Living with HIVT. A. Ajose0J. Aniekwena1V. S. Effoe2M. Simien3Division of General Internal Medicine, Department of Medicine, Morehouse School of Medicine, Atlanta, GA, USADivision of General Internal Medicine, Department of Medicine, Morehouse School of Medicine, Atlanta, GA, USADivision of General Internal Medicine, Department of Medicine, Morehouse School of Medicine, Atlanta, GA, USADivision of General Internal Medicine, Department of Medicine, Morehouse School of Medicine, Atlanta, GA, USAWe describe a case of a homosexual male with human immunodeficiency virus (HIV) and CD4 count of 246 presenting with acute severe bloody diarrhea. Infectious work up was negative, and colonoscopy revealed severe diffuse colonic ulcerations. Histopathologic analysis and Treponemal pallidum immunostaining confirmed the diagnosis of intestinal spirochetosis. There was no evidence of co-infection with other pathogens. His symptoms completely resolved after a 14-day course of metronidazole. This case is notable as colonic ulceration of any severity in patients living with HIV is rarely identified with intestinal spirochetosis. Hence, it should be considered in the differential diagnosis of colonic ulcerations.http://dx.doi.org/10.1155/2019/1504079 |
| spellingShingle | T. A. Ajose J. Aniekwena V. S. Effoe M. Simien Severe Human Intestinal Spirochetosis: An Unusual Cause of Diffuse Colonic Ulcerations in a Patient Living with HIV Case Reports in Gastrointestinal Medicine |
| title | Severe Human Intestinal Spirochetosis: An Unusual Cause of Diffuse Colonic Ulcerations in a Patient Living with HIV |
| title_full | Severe Human Intestinal Spirochetosis: An Unusual Cause of Diffuse Colonic Ulcerations in a Patient Living with HIV |
| title_fullStr | Severe Human Intestinal Spirochetosis: An Unusual Cause of Diffuse Colonic Ulcerations in a Patient Living with HIV |
| title_full_unstemmed | Severe Human Intestinal Spirochetosis: An Unusual Cause of Diffuse Colonic Ulcerations in a Patient Living with HIV |
| title_short | Severe Human Intestinal Spirochetosis: An Unusual Cause of Diffuse Colonic Ulcerations in a Patient Living with HIV |
| title_sort | severe human intestinal spirochetosis an unusual cause of diffuse colonic ulcerations in a patient living with hiv |
| url | http://dx.doi.org/10.1155/2019/1504079 |
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