Idiopathic Intrahepatic Cholestasis as an Unusual Presentation of Hodgkin’s Disease

Intrahepatic cholestasis in the form of paraneoplastic phenomena is an uncommon presentation of Hodgkin’s lymphoma (HL). Herein we report the diagnosis of mixed type HL-related idiopathic intrahepatic cholestasis in a 73-year-old man presenting with jaundice, after the inguinal lymph node biopsy ind...

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Main Authors: Hande Atalay, Banu Boyuk, Muhammet Ates, Aslan Celebi, Ismail Ekizoglu, Arzu A. Didik, Aysenur A. Igdem
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2015/987860
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author Hande Atalay
Banu Boyuk
Muhammet Ates
Aslan Celebi
Ismail Ekizoglu
Arzu A. Didik
Aysenur A. Igdem
author_facet Hande Atalay
Banu Boyuk
Muhammet Ates
Aslan Celebi
Ismail Ekizoglu
Arzu A. Didik
Aysenur A. Igdem
author_sort Hande Atalay
collection DOAJ
description Intrahepatic cholestasis in the form of paraneoplastic phenomena is an uncommon presentation of Hodgkin’s lymphoma (HL). Herein we report the diagnosis of mixed type HL-related idiopathic intrahepatic cholestasis in a 73-year-old man presenting with jaundice, after the inguinal lymph node biopsy indicative of mixed cellular type HL and liver biopsy consistent with intrahepatic cholestasis, following several diagnostic interventions including surgery for suspected extrahepatic obstructive cholestasis. Our findings emphasize the value of early liver biopsy in the diagnostic algorithm along with consideration of HL-related idiopathic intrahepatic cholestasis as a diagnosis of exclusion in cholestatic jaundice of obscure origin.
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institution Kabale University
issn 2090-6560
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language English
publishDate 2015-01-01
publisher Wiley
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series Case Reports in Hematology
spelling doaj-art-83cdd23c567f4725a37ed7c2985bbcc02025-08-20T03:37:37ZengWileyCase Reports in Hematology2090-65602090-65792015-01-01201510.1155/2015/987860987860Idiopathic Intrahepatic Cholestasis as an Unusual Presentation of Hodgkin’s DiseaseHande Atalay0Banu Boyuk1Muhammet Ates2Aslan Celebi3Ismail Ekizoglu4Arzu A. Didik5Aysenur A. Igdem6Department of Internal Medicine, Gaziosmanpasa Taksim Education and Research Hospital, 34240 Istanbul, TurkeyDepartment of Internal Medicine, Gaziosmanpasa Taksim Education and Research Hospital, 34240 Istanbul, TurkeyDepartment of Internal Medicine, Gaziosmanpasa Taksim Education and Research Hospital, 34240 Istanbul, TurkeyDepartment of Internal Medicine, Gaziosmanpasa Taksim Education and Research Hospital, 34240 Istanbul, TurkeyDepartment of Internal Medicine, Gaziosmanpasa Taksim Education and Research Hospital, 34240 Istanbul, TurkeyDepartment of Pathology, Gaziosmanpasa Taksim Education and Research Hospital, 34240 Istanbul, TurkeyDepartment of Pathology, Gaziosmanpasa Taksim Education and Research Hospital, 34240 Istanbul, TurkeyIntrahepatic cholestasis in the form of paraneoplastic phenomena is an uncommon presentation of Hodgkin’s lymphoma (HL). Herein we report the diagnosis of mixed type HL-related idiopathic intrahepatic cholestasis in a 73-year-old man presenting with jaundice, after the inguinal lymph node biopsy indicative of mixed cellular type HL and liver biopsy consistent with intrahepatic cholestasis, following several diagnostic interventions including surgery for suspected extrahepatic obstructive cholestasis. Our findings emphasize the value of early liver biopsy in the diagnostic algorithm along with consideration of HL-related idiopathic intrahepatic cholestasis as a diagnosis of exclusion in cholestatic jaundice of obscure origin.http://dx.doi.org/10.1155/2015/987860
spellingShingle Hande Atalay
Banu Boyuk
Muhammet Ates
Aslan Celebi
Ismail Ekizoglu
Arzu A. Didik
Aysenur A. Igdem
Idiopathic Intrahepatic Cholestasis as an Unusual Presentation of Hodgkin’s Disease
Case Reports in Hematology
title Idiopathic Intrahepatic Cholestasis as an Unusual Presentation of Hodgkin’s Disease
title_full Idiopathic Intrahepatic Cholestasis as an Unusual Presentation of Hodgkin’s Disease
title_fullStr Idiopathic Intrahepatic Cholestasis as an Unusual Presentation of Hodgkin’s Disease
title_full_unstemmed Idiopathic Intrahepatic Cholestasis as an Unusual Presentation of Hodgkin’s Disease
title_short Idiopathic Intrahepatic Cholestasis as an Unusual Presentation of Hodgkin’s Disease
title_sort idiopathic intrahepatic cholestasis as an unusual presentation of hodgkin s disease
url http://dx.doi.org/10.1155/2015/987860
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AT aslancelebi idiopathicintrahepaticcholestasisasanunusualpresentationofhodgkinsdisease
AT ismailekizoglu idiopathicintrahepaticcholestasisasanunusualpresentationofhodgkinsdisease
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