Aetiology of haemorrhagic cystitis: BK Polyomavirus and Adenovirus detection
This case report details haemorrhagic cystitis in a 49-year-old female with chronic lymphocytic leukaemia (CLL), recurrent haematuria and detected BK polyomavirus (BKPyV) and adenovirus (HAdV) in urine. During chemotherapy cycles, quantitative polymerase chain reaction (PCR) assays found high HAdV l...
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| Format: | Article |
| Language: | English |
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AOSIS
2025-02-01
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| Series: | Southern African Journal of Infectious Diseases |
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| Online Access: | https://sajid.co.za/index.php/sajid/article/view/685 |
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| author | Yoliswa Z. Chili Menzi B. Nkosi Nicky-Louise Byrne Moepeng J. Maseko Stephen N.J. Korsman Gert U. Van Zyl |
| author_facet | Yoliswa Z. Chili Menzi B. Nkosi Nicky-Louise Byrne Moepeng J. Maseko Stephen N.J. Korsman Gert U. Van Zyl |
| author_sort | Yoliswa Z. Chili |
| collection | DOAJ |
| description | This case report details haemorrhagic cystitis in a 49-year-old female with chronic lymphocytic leukaemia (CLL), recurrent haematuria and detected BK polyomavirus (BKPyV) and adenovirus (HAdV) in urine. During chemotherapy cycles, quantitative polymerase chain reaction (PCR) assays found high HAdV load, similar to a HAdV-B2 genotype 78, a rare genotype that is closely related to HAdV-11.
Contribution: Viral interactions reveal immune system vulnerabilities. |
| format | Article |
| id | doaj-art-83b1a89fc25a4c098b81703066887614 |
| institution | Kabale University |
| issn | 2312-0053 2313-1810 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | AOSIS |
| record_format | Article |
| series | Southern African Journal of Infectious Diseases |
| spelling | doaj-art-83b1a89fc25a4c098b817030668876142025-02-11T13:29:27ZengAOSISSouthern African Journal of Infectious Diseases2312-00532313-18102025-02-01401e1e410.4102/sajid.v40i1.685332Aetiology of haemorrhagic cystitis: BK Polyomavirus and Adenovirus detectionYoliswa Z. Chili0Menzi B. Nkosi1Nicky-Louise Byrne2Moepeng J. Maseko3Stephen N.J. Korsman4Gert U. Van Zyl5Department of Pathology, Division of Medical Virology, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa; and Department of Pathology, Division of Medical Virology, Faculty of Health Sciences, National Health Laboratory Service, Tygerberg Hospital, Cape TownDepartment of Pathology, Division of Medical Virology, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa; and Department of Pathology, Division of Medical Virology, Faculty of Health Sciences, National Health Laboratory Service, Tygerberg Hospital, Cape TownDepartment of Pathology, Division of Medical Virology, Faculty of Health Sciences, Stellenbosch University, Cape TownDepartment of Pathology, Division of Medical Virology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa; and Department of Pathology, Division of Medical Virology, Faculty of Health Sciences, National Health Laboratory Service, Groote Schuur Hospital, Cape TownDepartment of Pathology, Division of Medical Virology, Faculty of Health Sciences, University of Cape Town, Cape Town; and Department of Pathology, Division of Medical Virology, Faculty of Health Sciences, National Health Laboratory Service, Groote Schuur Hospital, Cape Town,Department of Pathology, Division of Medical Virology, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa; and Department of Pathology, Division of Medical Virology, Faculty of Health Sciences, National Health Laboratory Service, Tygerberg Hospital, Cape TownThis case report details haemorrhagic cystitis in a 49-year-old female with chronic lymphocytic leukaemia (CLL), recurrent haematuria and detected BK polyomavirus (BKPyV) and adenovirus (HAdV) in urine. During chemotherapy cycles, quantitative polymerase chain reaction (PCR) assays found high HAdV load, similar to a HAdV-B2 genotype 78, a rare genotype that is closely related to HAdV-11. Contribution: Viral interactions reveal immune system vulnerabilities.https://sajid.co.za/index.php/sajid/article/view/685haemorrhagic cystitis, cll, adenovirus, bk polyomavirus |
| spellingShingle | Yoliswa Z. Chili Menzi B. Nkosi Nicky-Louise Byrne Moepeng J. Maseko Stephen N.J. Korsman Gert U. Van Zyl Aetiology of haemorrhagic cystitis: BK Polyomavirus and Adenovirus detection Southern African Journal of Infectious Diseases haemorrhagic cystitis, cll, adenovirus, bk polyomavirus |
| title | Aetiology of haemorrhagic cystitis: BK Polyomavirus and Adenovirus detection |
| title_full | Aetiology of haemorrhagic cystitis: BK Polyomavirus and Adenovirus detection |
| title_fullStr | Aetiology of haemorrhagic cystitis: BK Polyomavirus and Adenovirus detection |
| title_full_unstemmed | Aetiology of haemorrhagic cystitis: BK Polyomavirus and Adenovirus detection |
| title_short | Aetiology of haemorrhagic cystitis: BK Polyomavirus and Adenovirus detection |
| title_sort | aetiology of haemorrhagic cystitis bk polyomavirus and adenovirus detection |
| topic | haemorrhagic cystitis, cll, adenovirus, bk polyomavirus |
| url | https://sajid.co.za/index.php/sajid/article/view/685 |
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