Aetiology of haemorrhagic cystitis: BK Polyomavirus and Adenovirus detection

This case report details haemorrhagic cystitis in a 49-year-old female with chronic lymphocytic leukaemia (CLL), recurrent haematuria and detected BK polyomavirus (BKPyV) and adenovirus (HAdV) in urine. During chemotherapy cycles, quantitative polymerase chain reaction (PCR) assays found high HAdV l...

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Bibliographic Details
Main Authors: Yoliswa Z. Chili, Menzi B. Nkosi, Nicky-Louise Byrne, Moepeng J. Maseko, Stephen N.J. Korsman, Gert U. Van Zyl
Format: Article
Language:English
Published: AOSIS 2025-02-01
Series:Southern African Journal of Infectious Diseases
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Online Access:https://sajid.co.za/index.php/sajid/article/view/685
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Summary:This case report details haemorrhagic cystitis in a 49-year-old female with chronic lymphocytic leukaemia (CLL), recurrent haematuria and detected BK polyomavirus (BKPyV) and adenovirus (HAdV) in urine. During chemotherapy cycles, quantitative polymerase chain reaction (PCR) assays found high HAdV load, similar to a HAdV-B2 genotype 78, a rare genotype that is closely related to HAdV-11. Contribution: Viral interactions reveal immune system vulnerabilities.
ISSN:2312-0053
2313-1810