Currents status of radiotracers for breast cancer imaging in PET

Radiolabeled molecules have become valuable tools in the diagnosis, monitoring, and treatment of cancer, particularly breast cancer. Through the use of radiotracers, clinicians can target specific tumor cells, assess microenvironments, and identify metastases. These radiopharmaceuticals, based on ra...

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Main Authors: Chloé Jean, Stéphane Roux, Abdelilah Aziz, Maxence Mocquery-corre, Rana Bazzi, Yacine Merrouche, Stéphane Dedieu, Nicolas Etique, Dimitri Papathanassiou, Jérôme Devy
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Translational Oncology
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Online Access:http://www.sciencedirect.com/science/article/pii/S193652332500035X
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author Chloé Jean
Stéphane Roux
Abdelilah Aziz
Maxence Mocquery-corre
Rana Bazzi
Yacine Merrouche
Stéphane Dedieu
Nicolas Etique
Dimitri Papathanassiou
Jérôme Devy
author_facet Chloé Jean
Stéphane Roux
Abdelilah Aziz
Maxence Mocquery-corre
Rana Bazzi
Yacine Merrouche
Stéphane Dedieu
Nicolas Etique
Dimitri Papathanassiou
Jérôme Devy
author_sort Chloé Jean
collection DOAJ
description Radiolabeled molecules have become valuable tools in the diagnosis, monitoring, and treatment of cancer, particularly breast cancer. Through the use of radiotracers, clinicians can target specific tumor cells, assess microenvironments, and identify metastases. These radiopharmaceuticals, based on radionuclides, enable both imaging and therapeutic applications, leading to personalized cancer treatment. Techniques such as PET, SPECT, and the use of nanoparticles for theranostics are at the forefront of innovation, offering improved precision in both diagnosis and therapy. This review explores the various ways in which radiotracers are leveraged in modern oncology, with a focus on breast cancer, and highlights recent advancements in targeted radionuclide therapy and nanoparticle-based applications.
format Article
id doaj-art-83ac3bc0985d409e8e22a9f7b6c8f512
institution Kabale University
issn 1936-5233
language English
publishDate 2025-03-01
publisher Elsevier
record_format Article
series Translational Oncology
spelling doaj-art-83ac3bc0985d409e8e22a9f7b6c8f5122025-02-08T05:00:05ZengElsevierTranslational Oncology1936-52332025-03-0153102304Currents status of radiotracers for breast cancer imaging in PETChloé Jean0Stéphane Roux1Abdelilah Aziz2Maxence Mocquery-corre3Rana Bazzi4Yacine Merrouche5Stéphane Dedieu6Nicolas Etique7Dimitri Papathanassiou8Jérôme Devy9Université de Reims Champagne Ardenne, UMR CNRS 7369 MEDyC, Reims, France; Université de Reims Champagne Ardenne, CRESTIC, Reims, FranceUniversité Marie et Louis Pasteur, CNRS, Chrono-environnement (UMR 6249), F-25000 Besançon, FranceUniversité de Reims Champagne Ardenne, UMR CNRS 7369 MEDyC, Reims, FranceUniversité de Reims Champagne Ardenne, UMR CNRS 7369 MEDyC, Reims, FranceUniversité Marie et Louis Pasteur, CNRS, Chrono-environnement (UMR 6249), F-25000 Besançon, FranceInstitut Godinot, Reims, FranceUniversité de Reims Champagne Ardenne, UMR CNRS 7369 MEDyC, Reims, FranceUniversité de Reims Champagne Ardenne, UMR CNRS 7369 MEDyC, Reims, FranceInstitut Godinot, Reims, France; Université de Reims Champagne Ardenne, CRESTIC, Reims, FranceUniversité de Reims Champagne Ardenne, UMR CNRS 7369 MEDyC, Reims, France; Corresponding author.Radiolabeled molecules have become valuable tools in the diagnosis, monitoring, and treatment of cancer, particularly breast cancer. Through the use of radiotracers, clinicians can target specific tumor cells, assess microenvironments, and identify metastases. These radiopharmaceuticals, based on radionuclides, enable both imaging and therapeutic applications, leading to personalized cancer treatment. Techniques such as PET, SPECT, and the use of nanoparticles for theranostics are at the forefront of innovation, offering improved precision in both diagnosis and therapy. This review explores the various ways in which radiotracers are leveraged in modern oncology, with a focus on breast cancer, and highlights recent advancements in targeted radionuclide therapy and nanoparticle-based applications.http://www.sciencedirect.com/science/article/pii/S193652332500035XRadiotracersBreast cancerRadiopharmaceuticalsTargeted radionuclide therapyNanoparticles
spellingShingle Chloé Jean
Stéphane Roux
Abdelilah Aziz
Maxence Mocquery-corre
Rana Bazzi
Yacine Merrouche
Stéphane Dedieu
Nicolas Etique
Dimitri Papathanassiou
Jérôme Devy
Currents status of radiotracers for breast cancer imaging in PET
Translational Oncology
Radiotracers
Breast cancer
Radiopharmaceuticals
Targeted radionuclide therapy
Nanoparticles
title Currents status of radiotracers for breast cancer imaging in PET
title_full Currents status of radiotracers for breast cancer imaging in PET
title_fullStr Currents status of radiotracers for breast cancer imaging in PET
title_full_unstemmed Currents status of radiotracers for breast cancer imaging in PET
title_short Currents status of radiotracers for breast cancer imaging in PET
title_sort currents status of radiotracers for breast cancer imaging in pet
topic Radiotracers
Breast cancer
Radiopharmaceuticals
Targeted radionuclide therapy
Nanoparticles
url http://www.sciencedirect.com/science/article/pii/S193652332500035X
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