Net survival of women diagnosed with breast tumours: a population-based study in Switzerland
AIMS OF THE STUDY: Although the incidence of breast carcinoma in situ has been increasing, the prognosis of breast carcinoma in situ patients has not been extensively investigated. Thus, we aimed to compare the characteristics of invasive breast tumours based on whether or not they were preceded by...
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| Format: | Article |
| Language: | English |
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SMW supporting association (Trägerverein Swiss Medical Weekly SMW)
2023-08-01
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| Series: | Swiss Medical Weekly |
| Online Access: | https://smw.ch/index.php/smw/article/view/3469 |
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| author | Nena Karavasiloglou Eleftheria Michalopoulou Manuela Limam Dimitri Korol Miriam Wanner Sabine Rohrmann |
| author_facet | Nena Karavasiloglou Eleftheria Michalopoulou Manuela Limam Dimitri Korol Miriam Wanner Sabine Rohrmann |
| author_sort | Nena Karavasiloglou |
| collection | DOAJ |
| description |
AIMS OF THE STUDY: Although the incidence of breast carcinoma in situ has been increasing, the prognosis of breast carcinoma in situ patients has not been extensively investigated. Thus, we aimed to compare the characteristics of invasive breast tumours based on whether or not they were preceded by a breast carcinoma in situ and to estimate the 5-year net survival of patients diagnosed with different breast tumours.
METHODS: Data from women diagnosed with breast tumours between 2003 and 2016 were used in our analyses. Net survival analyses were performed using inverse probability of censoring weights (nonparametric Pohar Perme estimator). Under certain assumptions, differences in survival between the cancer population and the general population can be considered to be attributable to the cancer diagnosis (NS).
RESULTS: Descriptive observation of tumour characteristics indicated that invasive breast tumours following a breast carcinoma in situ were more frequently detected at an earlier stage and had less missing information in tumour-specific variables, compared to invasive breast tumours not preceded by a breast carcinoma in situ. Breast carcinoma in situ patients had a 5-year net survival of 1.02 (95% CI: 1.01–1.03), whereas patients diagnosed with invasive breast cancer without a recorded breast carcinoma in situ had a 5-year net survival of 0.89 (95% CI: 0.88–0.90). Patients diagnosed first with breast carcinoma in situ and then with invasive breast cancer had a 5-year net survival of 0.92 (95% CI: 0.85–1.01).
CONCLUSION: Invasive breast tumours that were preceded by a breast carcinoma in situ were detected more frequently at an earlier stage, compared to those that were not. The estimated 5-year net survival of patients with breast tumours was good.
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| format | Article |
| id | doaj-art-83a6851f89fa4f6da4f313fb58f4c2c5 |
| institution | OA Journals |
| issn | 1424-3997 |
| language | English |
| publishDate | 2023-08-01 |
| publisher | SMW supporting association (Trägerverein Swiss Medical Weekly SMW) |
| record_format | Article |
| series | Swiss Medical Weekly |
| spelling | doaj-art-83a6851f89fa4f6da4f313fb58f4c2c52025-08-20T02:23:53ZengSMW supporting association (Trägerverein Swiss Medical Weekly SMW)Swiss Medical Weekly1424-39972023-08-01153810.57187/smw.2023.40087Net survival of women diagnosed with breast tumours: a population-based study in SwitzerlandNena Karavasiloglou Eleftheria Michalopoulou Manuela LimamDimitri KorolMiriam WannerSabine Rohrmann AIMS OF THE STUDY: Although the incidence of breast carcinoma in situ has been increasing, the prognosis of breast carcinoma in situ patients has not been extensively investigated. Thus, we aimed to compare the characteristics of invasive breast tumours based on whether or not they were preceded by a breast carcinoma in situ and to estimate the 5-year net survival of patients diagnosed with different breast tumours. METHODS: Data from women diagnosed with breast tumours between 2003 and 2016 were used in our analyses. Net survival analyses were performed using inverse probability of censoring weights (nonparametric Pohar Perme estimator). Under certain assumptions, differences in survival between the cancer population and the general population can be considered to be attributable to the cancer diagnosis (NS). RESULTS: Descriptive observation of tumour characteristics indicated that invasive breast tumours following a breast carcinoma in situ were more frequently detected at an earlier stage and had less missing information in tumour-specific variables, compared to invasive breast tumours not preceded by a breast carcinoma in situ. Breast carcinoma in situ patients had a 5-year net survival of 1.02 (95% CI: 1.01–1.03), whereas patients diagnosed with invasive breast cancer without a recorded breast carcinoma in situ had a 5-year net survival of 0.89 (95% CI: 0.88–0.90). Patients diagnosed first with breast carcinoma in situ and then with invasive breast cancer had a 5-year net survival of 0.92 (95% CI: 0.85–1.01). CONCLUSION: Invasive breast tumours that were preceded by a breast carcinoma in situ were detected more frequently at an earlier stage, compared to those that were not. The estimated 5-year net survival of patients with breast tumours was good. https://smw.ch/index.php/smw/article/view/3469 |
| spellingShingle | Nena Karavasiloglou Eleftheria Michalopoulou Manuela Limam Dimitri Korol Miriam Wanner Sabine Rohrmann Net survival of women diagnosed with breast tumours: a population-based study in Switzerland Swiss Medical Weekly |
| title | Net survival of women diagnosed with breast tumours: a population-based study in Switzerland |
| title_full | Net survival of women diagnosed with breast tumours: a population-based study in Switzerland |
| title_fullStr | Net survival of women diagnosed with breast tumours: a population-based study in Switzerland |
| title_full_unstemmed | Net survival of women diagnosed with breast tumours: a population-based study in Switzerland |
| title_short | Net survival of women diagnosed with breast tumours: a population-based study in Switzerland |
| title_sort | net survival of women diagnosed with breast tumours a population based study in switzerland |
| url | https://smw.ch/index.php/smw/article/view/3469 |
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