Advances in non-small cell lung cancer mechanomedicine: deciphering the signaling networks that govern tumor-TME interactions

Advances in non-small cell lung cancer mechanomedicine: deciphering the signaling networks that govern tumor-TME interactions

Abstract Cells from the tumor microenvironment (TME) interact with tumor cells in non-small cell lung cancer (NSCLC) to form a reciprocal crosstalk which influences tumor growth, proliferation, metastasis and multidrug response. This crosstalk is modulated by TME mechanical inputs, which elicit the...

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Bibliographic Details
Main Authors: Antonios N. Gargalionis, Kostas A. Papavassiliou, Efthimia K. Basdra, Athanasios G. Papavassiliou
Format: Article
Language:English
Published: BMC 2024-11-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Non-small cell lung cancer
Tumor microenvironment
Mechanomedicine
Mechanosignaling
Mechanotransduction
YAP
Online Access:https://doi.org/10.1186/s13046-024-03242-1
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