Identification and validation of tissue-based gene biomarkers for acute intestinal graft-versus-host disease(AIGVHD)

Identification and validation of tissue-based gene biomarkers for acute intestinal graft-versus-host disease(AIGVHD)

BackgroundAcute intestinal graft-versus-host disease (AIGVHD) is a common complication of allogeneic hematopoietic stem cell transplantation (allo HSCT) with a high mortality rate. The primary aim of the present study is to identify tissue-based gene biomarkers pertinent to AIGVHD, thereby facilitat...

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Bibliographic Details
Main Authors: Hong Chen, Liyu Fu, Liying Liu, Yunyan He
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
Subjects:
aGVHD
Allo HSCT
gene biomarkers
immune cell infiltration
machine learning
aGVHD mouse model
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1574904/full
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