Respiratory Flora Intervention: A New Strategy for the Prevention and Treatment of Occupationally Related Respiratory Allergy in Healthcare Workers
Occupational allergic respiratory disease in healthcare workers due to occupational exposure has received widespread attention. At the same time, evidence of altered respiratory flora associated with the development of allergy has been found in relevant epidemiologic studies. It is of concern that t...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2024-12-01
|
| Series: | Microorganisms |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-2607/12/12/2653 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850060106901749760 |
|---|---|
| author | Linglin Gao Xi Chen Ziyi Jiang Jie Zhu Qiang Wang |
| author_facet | Linglin Gao Xi Chen Ziyi Jiang Jie Zhu Qiang Wang |
| author_sort | Linglin Gao |
| collection | DOAJ |
| description | Occupational allergic respiratory disease in healthcare workers due to occupational exposure has received widespread attention. At the same time, evidence of altered respiratory flora associated with the development of allergy has been found in relevant epidemiologic studies. It is of concern that the composition of nasopharyngeal flora in healthcare workers differs significantly from that of non-healthcare workers due to occupational factors, with a particularly high prevalence of carriage of pathogenic and drug-resistant bacteria. Recent studies have found that interventions with upper respiratory tract probiotics can significantly reduce the incidence of respiratory allergies and infections. We searched PubMed and other databases to describe the burden of allergic respiratory disease and altered respiratory flora in healthcare workers in this narrative review, and we summarize the mechanisms and current state of clinical research on the use of flora interventions to ameliorate respiratory allergy, with the aim of providing a new direction for protecting the respiratory health of healthcare workers. |
| format | Article |
| id | doaj-art-83972f0476014befbae0eaec213dbb3b |
| institution | DOAJ |
| issn | 2076-2607 |
| language | English |
| publishDate | 2024-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj-art-83972f0476014befbae0eaec213dbb3b2025-08-20T02:50:41ZengMDPI AGMicroorganisms2076-26072024-12-011212265310.3390/microorganisms12122653Respiratory Flora Intervention: A New Strategy for the Prevention and Treatment of Occupationally Related Respiratory Allergy in Healthcare WorkersLinglin Gao0Xi Chen1Ziyi Jiang2Jie Zhu3Qiang Wang4Hubei Province Key Laboratory of Occupational Hazard Identification and Control, Institute of Infection, Immunology and Tumor Microenvironment, Medical College, Wuhan University of Science and Technology, Wuhan 430065, ChinaHubei Province Key Laboratory of Occupational Hazard Identification and Control, Institute of Infection, Immunology and Tumor Microenvironment, Medical College, Wuhan University of Science and Technology, Wuhan 430065, ChinaHubei Province Key Laboratory of Occupational Hazard Identification and Control, Institute of Infection, Immunology and Tumor Microenvironment, Medical College, Wuhan University of Science and Technology, Wuhan 430065, ChinaHubei Province Key Laboratory of Occupational Hazard Identification and Control, Institute of Infection, Immunology and Tumor Microenvironment, Medical College, Wuhan University of Science and Technology, Wuhan 430065, ChinaHubei Province Key Laboratory of Occupational Hazard Identification and Control, Institute of Infection, Immunology and Tumor Microenvironment, Medical College, Wuhan University of Science and Technology, Wuhan 430065, ChinaOccupational allergic respiratory disease in healthcare workers due to occupational exposure has received widespread attention. At the same time, evidence of altered respiratory flora associated with the development of allergy has been found in relevant epidemiologic studies. It is of concern that the composition of nasopharyngeal flora in healthcare workers differs significantly from that of non-healthcare workers due to occupational factors, with a particularly high prevalence of carriage of pathogenic and drug-resistant bacteria. Recent studies have found that interventions with upper respiratory tract probiotics can significantly reduce the incidence of respiratory allergies and infections. We searched PubMed and other databases to describe the burden of allergic respiratory disease and altered respiratory flora in healthcare workers in this narrative review, and we summarize the mechanisms and current state of clinical research on the use of flora interventions to ameliorate respiratory allergy, with the aim of providing a new direction for protecting the respiratory health of healthcare workers.https://www.mdpi.com/2076-2607/12/12/2653flora interventionshealthcare workersoccupational exposureoccupational allergic respiratory diseases |
| spellingShingle | Linglin Gao Xi Chen Ziyi Jiang Jie Zhu Qiang Wang Respiratory Flora Intervention: A New Strategy for the Prevention and Treatment of Occupationally Related Respiratory Allergy in Healthcare Workers Microorganisms flora interventions healthcare workers occupational exposure occupational allergic respiratory diseases |
| title | Respiratory Flora Intervention: A New Strategy for the Prevention and Treatment of Occupationally Related Respiratory Allergy in Healthcare Workers |
| title_full | Respiratory Flora Intervention: A New Strategy for the Prevention and Treatment of Occupationally Related Respiratory Allergy in Healthcare Workers |
| title_fullStr | Respiratory Flora Intervention: A New Strategy for the Prevention and Treatment of Occupationally Related Respiratory Allergy in Healthcare Workers |
| title_full_unstemmed | Respiratory Flora Intervention: A New Strategy for the Prevention and Treatment of Occupationally Related Respiratory Allergy in Healthcare Workers |
| title_short | Respiratory Flora Intervention: A New Strategy for the Prevention and Treatment of Occupationally Related Respiratory Allergy in Healthcare Workers |
| title_sort | respiratory flora intervention a new strategy for the prevention and treatment of occupationally related respiratory allergy in healthcare workers |
| topic | flora interventions healthcare workers occupational exposure occupational allergic respiratory diseases |
| url | https://www.mdpi.com/2076-2607/12/12/2653 |
| work_keys_str_mv | AT linglingao respiratoryflorainterventionanewstrategyforthepreventionandtreatmentofoccupationallyrelatedrespiratoryallergyinhealthcareworkers AT xichen respiratoryflorainterventionanewstrategyforthepreventionandtreatmentofoccupationallyrelatedrespiratoryallergyinhealthcareworkers AT ziyijiang respiratoryflorainterventionanewstrategyforthepreventionandtreatmentofoccupationallyrelatedrespiratoryallergyinhealthcareworkers AT jiezhu respiratoryflorainterventionanewstrategyforthepreventionandtreatmentofoccupationallyrelatedrespiratoryallergyinhealthcareworkers AT qiangwang respiratoryflorainterventionanewstrategyforthepreventionandtreatmentofoccupationallyrelatedrespiratoryallergyinhealthcareworkers |