Withaferin A-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species.
Withaferin A (WA), a promising anticancer constituent of Ayurvedic medicinal plant Withania somnifera, inhibits growth of MDA-MB-231 and MCF-7 human breast cancer cells in culture and MDA-MB-231 xenografts in vivo in association with apoptosis induction, but the mechanism of cell death is not fully...
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| Main Authors: | Eun-Ryeong Hahm, Michelle B Moura, Eric E Kelley, Bennett Van Houten, Sruti Shiva, Shivendra V Singh |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2011-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0023354&type=printable |
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