Spatially distributed effects of mental exhaustion on resting-state FMRI networks.
Brain activity during rest is spatially coherent over functional connectivity networks called resting-state networks. In resting-state functional magnetic resonance imaging, independent component analysis yields spatially distributed network representations reflecting distinct mental processes, such...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0094222&type=printable |
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| author | Fabrizio Esposito Tobias Otto Fred R H Zijlstra Rainer Goebel |
| author_facet | Fabrizio Esposito Tobias Otto Fred R H Zijlstra Rainer Goebel |
| author_sort | Fabrizio Esposito |
| collection | DOAJ |
| description | Brain activity during rest is spatially coherent over functional connectivity networks called resting-state networks. In resting-state functional magnetic resonance imaging, independent component analysis yields spatially distributed network representations reflecting distinct mental processes, such as intrinsic (default) or extrinsic (executive) attention, and sensory inhibition or excitation. These aspects can be related to different treatments or subjective experiences. Among these, exhaustion is a common psychological state induced by prolonged mental performance. Using repeated functional magnetic resonance imaging sessions and spatial independent component analysis, we explored the effect of several hours of sustained cognitive performances on the resting human brain. Resting-state functional magnetic resonance imaging was performed on the same healthy volunteers in two days, with and without, and before, during and after, an intensive psychological treatment (skill training and sustained practice with a flight simulator). After each scan, subjects rated their level of exhaustion and performed an N-back task to evaluate eventual decrease in cognitive performance. Spatial maps of selected resting-state network components were statistically evaluated across time points to detect possible changes induced by the sustained mental performance. The intensive treatment had a significant effect on exhaustion and effort ratings, but no effects on N-back performances. Significant changes in the most exhausted state were observed in the early visual processing and the anterior default mode networks (enhancement) and in the fronto-parietal executive networks (suppression), suggesting that mental exhaustion is associated with a more idling brain state and that internal attention processes are facilitated to the detriment of more extrinsic processes. The described application may inspire future indicators of the level of fatigue in the neural attention system. |
| format | Article |
| id | doaj-art-837939dda6fb44e2a199f2b8ca7a2207 |
| institution | DOAJ |
| issn | 1932-6203 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-837939dda6fb44e2a199f2b8ca7a22072025-08-20T03:11:55ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0194e9422210.1371/journal.pone.0094222Spatially distributed effects of mental exhaustion on resting-state FMRI networks.Fabrizio EspositoTobias OttoFred R H ZijlstraRainer GoebelBrain activity during rest is spatially coherent over functional connectivity networks called resting-state networks. In resting-state functional magnetic resonance imaging, independent component analysis yields spatially distributed network representations reflecting distinct mental processes, such as intrinsic (default) or extrinsic (executive) attention, and sensory inhibition or excitation. These aspects can be related to different treatments or subjective experiences. Among these, exhaustion is a common psychological state induced by prolonged mental performance. Using repeated functional magnetic resonance imaging sessions and spatial independent component analysis, we explored the effect of several hours of sustained cognitive performances on the resting human brain. Resting-state functional magnetic resonance imaging was performed on the same healthy volunteers in two days, with and without, and before, during and after, an intensive psychological treatment (skill training and sustained practice with a flight simulator). After each scan, subjects rated their level of exhaustion and performed an N-back task to evaluate eventual decrease in cognitive performance. Spatial maps of selected resting-state network components were statistically evaluated across time points to detect possible changes induced by the sustained mental performance. The intensive treatment had a significant effect on exhaustion and effort ratings, but no effects on N-back performances. Significant changes in the most exhausted state were observed in the early visual processing and the anterior default mode networks (enhancement) and in the fronto-parietal executive networks (suppression), suggesting that mental exhaustion is associated with a more idling brain state and that internal attention processes are facilitated to the detriment of more extrinsic processes. The described application may inspire future indicators of the level of fatigue in the neural attention system.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0094222&type=printable |
| spellingShingle | Fabrizio Esposito Tobias Otto Fred R H Zijlstra Rainer Goebel Spatially distributed effects of mental exhaustion on resting-state FMRI networks. PLoS ONE |
| title | Spatially distributed effects of mental exhaustion on resting-state FMRI networks. |
| title_full | Spatially distributed effects of mental exhaustion on resting-state FMRI networks. |
| title_fullStr | Spatially distributed effects of mental exhaustion on resting-state FMRI networks. |
| title_full_unstemmed | Spatially distributed effects of mental exhaustion on resting-state FMRI networks. |
| title_short | Spatially distributed effects of mental exhaustion on resting-state FMRI networks. |
| title_sort | spatially distributed effects of mental exhaustion on resting state fmri networks |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0094222&type=printable |
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