Association between metabolic score for visceral fat and psoriasis: findings from NHANES
Abstract Background Psoriasis is a persistent inflammatory skin condition. Several studies have revealed that obesity significantly contributes to both the initiation and advancement of psoriasis. The metabolic score for visceral fat (METS-VF) represents an innovative measure designed to forecast vi...
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2025-08-01
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| Series: | European Journal of Medical Research |
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| Online Access: | https://doi.org/10.1186/s40001-025-03002-7 |
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| author | Xinyi Shao Yi Ou Qian Liu Yidian Fu Yan Pan Aijun Chen Genlong Bai Jingbo Zhang |
| author_facet | Xinyi Shao Yi Ou Qian Liu Yidian Fu Yan Pan Aijun Chen Genlong Bai Jingbo Zhang |
| author_sort | Xinyi Shao |
| collection | DOAJ |
| description | Abstract Background Psoriasis is a persistent inflammatory skin condition. Several studies have revealed that obesity significantly contributes to both the initiation and advancement of psoriasis. The metabolic score for visceral fat (METS-VF) represents an innovative measure designed to forecast visceral obesity, integrating factors such as insulin resistance metabolic score, waist-to-hip ratio (WHR), age, and gender. The present study aimed to investigate the association between METS-VF and psoriasis prevalence, using information gathered from the National Health and Nutrition Examination Survey (NHANES). Methods This study utilized the data from a nationally representative cohort of 8023 adults from NHANES from 2003–2006 to 2009–2014, of which 234 declared a psoriasis history. Multivariate logistic regression analysis and restricted cubic spline (RCS) analyses were used to investigate the association between METS-VF and psoriasis, followed by subgroup analysis to identify populations that may exhibit higher sensitivity. Results After adjusting for confounding variables, the results of the multivariate logistic regression analysis showed a significant positive association between METS-VF and the risk of psoriasis. One-unit increasement in METS-VF corresponded to a 47% rise in psoriasis risk (odds ratio [OR] = 1.47, 95% confidence interval [CI] = 1.10–1.96). Finally, the results were uniform across all subgroups (P for interaction > 0.05). The results from the RCS analysis indicated a notable linear association. Conclusion This research indicated that elevated levels of METS-VF are linked to a higher occurrence of psoriasis, suggesting the potential of METS-VF as a predictive anthropometric index for assessing the risk of developing psoriasis. |
| format | Article |
| id | doaj-art-837389db2fdc4739bbb4a523d5aec094 |
| institution | Kabale University |
| issn | 2047-783X |
| language | English |
| publishDate | 2025-08-01 |
| publisher | BMC |
| record_format | Article |
| series | European Journal of Medical Research |
| spelling | doaj-art-837389db2fdc4739bbb4a523d5aec0942025-08-20T04:01:53ZengBMCEuropean Journal of Medical Research2047-783X2025-08-013011910.1186/s40001-025-03002-7Association between metabolic score for visceral fat and psoriasis: findings from NHANESXinyi Shao0Yi Ou1Qian Liu2Yidian Fu3Yan Pan4Aijun Chen5Genlong Bai6Jingbo Zhang7Department of Dermatology, The First Affiliated Hospital of Chongqing Medical UniversityDepartment of Dermatology, The First Affiliated Hospital of Chongqing Medical UniversityDepartment of Dermatology, The First Affiliated Hospital of Chongqing Medical UniversityGraduate School of Hebei Medical UniversityChongqing Medical UniversityDepartment of Dermatology, The First Affiliated Hospital of Chongqing Medical UniversityDepartment of Dermatology, The First Affiliated Hospital of Chongqing Medical UniversityDepartment of Dermatology, The First Affiliated Hospital of Chongqing Medical UniversityAbstract Background Psoriasis is a persistent inflammatory skin condition. Several studies have revealed that obesity significantly contributes to both the initiation and advancement of psoriasis. The metabolic score for visceral fat (METS-VF) represents an innovative measure designed to forecast visceral obesity, integrating factors such as insulin resistance metabolic score, waist-to-hip ratio (WHR), age, and gender. The present study aimed to investigate the association between METS-VF and psoriasis prevalence, using information gathered from the National Health and Nutrition Examination Survey (NHANES). Methods This study utilized the data from a nationally representative cohort of 8023 adults from NHANES from 2003–2006 to 2009–2014, of which 234 declared a psoriasis history. Multivariate logistic regression analysis and restricted cubic spline (RCS) analyses were used to investigate the association between METS-VF and psoriasis, followed by subgroup analysis to identify populations that may exhibit higher sensitivity. Results After adjusting for confounding variables, the results of the multivariate logistic regression analysis showed a significant positive association between METS-VF and the risk of psoriasis. One-unit increasement in METS-VF corresponded to a 47% rise in psoriasis risk (odds ratio [OR] = 1.47, 95% confidence interval [CI] = 1.10–1.96). Finally, the results were uniform across all subgroups (P for interaction > 0.05). The results from the RCS analysis indicated a notable linear association. Conclusion This research indicated that elevated levels of METS-VF are linked to a higher occurrence of psoriasis, suggesting the potential of METS-VF as a predictive anthropometric index for assessing the risk of developing psoriasis.https://doi.org/10.1186/s40001-025-03002-7Metabolic score for visceral fatPsoriasisCross-sectional studyNHANES |
| spellingShingle | Xinyi Shao Yi Ou Qian Liu Yidian Fu Yan Pan Aijun Chen Genlong Bai Jingbo Zhang Association between metabolic score for visceral fat and psoriasis: findings from NHANES European Journal of Medical Research Metabolic score for visceral fat Psoriasis Cross-sectional study NHANES |
| title | Association between metabolic score for visceral fat and psoriasis: findings from NHANES |
| title_full | Association between metabolic score for visceral fat and psoriasis: findings from NHANES |
| title_fullStr | Association between metabolic score for visceral fat and psoriasis: findings from NHANES |
| title_full_unstemmed | Association between metabolic score for visceral fat and psoriasis: findings from NHANES |
| title_short | Association between metabolic score for visceral fat and psoriasis: findings from NHANES |
| title_sort | association between metabolic score for visceral fat and psoriasis findings from nhanes |
| topic | Metabolic score for visceral fat Psoriasis Cross-sectional study NHANES |
| url | https://doi.org/10.1186/s40001-025-03002-7 |
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