Hypothermia Mitigates Renal Fibrosis Through the Upregulation of PGC-1α After Ischemia–Reperfusion Injury

Hypothermia Mitigates Renal Fibrosis Through the Upregulation of PGC-1α After Ischemia–Reperfusion Injury

<b>Background:</b> Hypothermia has been previously reported to ameliorate acute renal injury induced by ischemia–reperfusion injury (IRI). However, its protective effects against subsequent renal fibrosis remain unclear. <b>Objectives</b>: The aim of this study was to determi...

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Bibliographic Details
Main Authors: Dabi Kim, Suyeon Han, Hyunsu Choi, Yoon-Kyung Chang, Dae Eun Choi
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Biomedicines
Subjects:
hypothermic protection
renal fibrosis
ischemia–reperfusion injury
Online Access:https://www.mdpi.com/2227-9059/13/6/1337
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