Analysis of biological and genetic stability of tick-borne encephalitis strain 205 used in the production of tick-borne encephalitis vaccines EnceVir and EnceVir Neo for children

Analysis of biological and genetic stability of tick-borne encephalitis strain 205 used in the production of tick-borne encephalitis vaccines EnceVir and EnceVir Neo for children

The article presents the results of a long-term study of biological and genetic stability of tick-borne encephalitis strain 205 which is used by the FSUE «SPA «Microgen» to produce tick-borne encephalitis vaccines EnceVir (for adults) and EnceVir Neo for children, both of which are tissue cultured,...

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Bibliographic Details
Main Authors:	M. S. Vorobyeva, G. M. Ignatyev, N. A. Netesova, E. V. Otrashevskaya, N. Kh. Stavitskaya, M. S. Shcherbinina, K. A. Sarkisyan, V. A. Shevtsov, A. V. Rukavishnikov, V. P. Bondarev
Format:	Article
Language:	Russian
Published:	Ministry of Health of the Russian Federation. Federal State Budgetary Institution «Scientific Centre for Expert Evaluation of Medicinal Products» 2018-02-01
Series:	Биопрепараты: Профилактика, диагностика, лечение
Subjects:	клещевой энцефалит вакцинация производство вакцин клещевого энцефалита биологическая и генетическая стабильность подлинность в реакции биологической нейтрализации пассажи через мозг аутбредных белых мышей полимеразная цепная реакция праймеры секвенирование tick-borne encephalitis vaccination production of tick-borne encephalitis vaccines biological and genetic stability identification in a biological neutralization assay outbred white mouse brain passage polymerase chain reaction primers sequencing
Online Access:	https://www.biopreparations.ru/jour/article/view/87
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