Modulation of microglial phagocytosis via the GAS6-MERTK pathway regulates pathological angiogenesis in the mouse oxygen-induced retinopathy model

Abstract Ischemic retinopathies (IR) are major causes of blindness worldwide. They are characterized by an exuberant hypoxia-driven pathological neovascularization (NV). While it is well accepted that immune cells contribute to both physiological and pathological retinal angiogenesis, our knowledge...

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Bibliographic Details
Main Authors: Canelif Yilmaz, Irina Korovina, Anke Witt, Farid Abdallah, Bianca Müller, Carmen Hentsche, Anika Fleischhauer, Stephan Speier, Andreas Deussen, Anne Klotzsche - von Ameln
Format: Article
Language:English
Published: Nature Publishing Group 2025-06-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-025-07744-4
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