Modulation of microglial phagocytosis via the GAS6-MERTK pathway regulates pathological angiogenesis in the mouse oxygen-induced retinopathy model
Abstract Ischemic retinopathies (IR) are major causes of blindness worldwide. They are characterized by an exuberant hypoxia-driven pathological neovascularization (NV). While it is well accepted that immune cells contribute to both physiological and pathological retinal angiogenesis, our knowledge...
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| Main Authors: | Canelif Yilmaz, Irina Korovina, Anke Witt, Farid Abdallah, Bianca Müller, Carmen Hentsche, Anika Fleischhauer, Stephan Speier, Andreas Deussen, Anne Klotzsche - von Ameln |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2025-06-01
|
| Series: | Cell Death and Disease |
| Online Access: | https://doi.org/10.1038/s41419-025-07744-4 |
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