Determination of Magnesium Isotopic Composition of Plant Chlorophylls Based on HPLC and MC-ICP-MS

The accurate determination of magnesium isotope values of chlorophyll a and chlorophyll b is particularly important for the study of magnesium biosynthesis pathways during chlorophyll formation. HPLC is required before MC-ICP-MS can be utilized, but HPLC lacks a method for separating chlorophylls. T...

Full description

Saved in:
Bibliographic Details
Main Authors: Zihan AN, Hongyu ZHANG, Jiaxin YIN, Pan ZHANG, Min YAO, Kangjun HUANG
Format: Article
Language:English
Published: Science Press, PR China 2024-05-01
Series:Yankuang ceshi
Subjects:
Online Access:http://www.ykcs.ac.cn/article/doi/10.15898/j.ykcs.202208300161
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850235732938981376
author Zihan AN
Hongyu ZHANG
Jiaxin YIN
Pan ZHANG
Min YAO
Kangjun HUANG
author_facet Zihan AN
Hongyu ZHANG
Jiaxin YIN
Pan ZHANG
Min YAO
Kangjun HUANG
author_sort Zihan AN
collection DOAJ
description The accurate determination of magnesium isotope values of chlorophyll a and chlorophyll b is particularly important for the study of magnesium biosynthesis pathways during chlorophyll formation. HPLC is required before MC-ICP-MS can be utilized, but HPLC lacks a method for separating chlorophylls. Therefore, it is necessary to develop a set of methods for separating plant chlorophyll a and chlorophyll b. The samples separated by this method are suitable for magnesium isotope determination by MC-ICP-MS. Based on the detection wavelength of 665nm and C18 column (7.6mm×250mm, 5μm), the HPLC conditions were optimized by three-factor and three-level orthogonal design to obtain the required parameters. The correlation coefficients of chlorophyll a and chlorophyll b standard curves in the concentration range of 5−50mg/L were greater than 0.9996, the detection limits were 0.40−1.09mg/L, the quantification limits were 1.22−3.31mg/L, the relative standard deviation was less than 8.10%, and the recoveries were 91.92%−111.11%. The magnesium isotope data of the isolated samples also showed that the column temperature of 25℃, flow rate of 1mL/min, and methanol-acetone (80∶20, V/V) mobile phase were reliable as HPLC separation conditions. The method established in this paper provides technical support for the separation of chlorophyll a and chlorophyll b in plants, and the separated samples can be used for magnesium isotope determination. The BRIEF REPORT is available for this paper at http://www.ykcs.ac.cn/en/article/doi/10.15898/j.ykcs.202208300161.
format Article
id doaj-art-8367141ba5b044188287655ec60dabf6
institution OA Journals
issn 0254-5357
language English
publishDate 2024-05-01
publisher Science Press, PR China
record_format Article
series Yankuang ceshi
spelling doaj-art-8367141ba5b044188287655ec60dabf62025-08-20T02:02:09ZengScience Press, PR ChinaYankuang ceshi0254-53572024-05-0143347648610.15898/j.ykcs.202208300161yk202208300161Determination of Magnesium Isotopic Composition of Plant Chlorophylls Based on HPLC and MC-ICP-MSZihan AN0Hongyu ZHANG1Jiaxin YIN2Pan ZHANG3Min YAO4Kangjun HUANG5State Key Laboratory of Continental Dynamics, Department of Geology, Northwest University, Xi’an 710069, ChinaState Key Laboratory of Continental Dynamics, Department of Geology, Northwest University, Xi’an 710069, ChinaState Key Laboratory of Continental Dynamics, Department of Geology, Northwest University, Xi’an 710069, ChinaState Key Laboratory of Continental Dynamics, Department of Geology, Northwest University, Xi’an 710069, ChinaState Key Laboratory of Continental Dynamics, Department of Geology, Northwest University, Xi’an 710069, ChinaState Key Laboratory of Continental Dynamics, Department of Geology, Northwest University, Xi’an 710069, ChinaThe accurate determination of magnesium isotope values of chlorophyll a and chlorophyll b is particularly important for the study of magnesium biosynthesis pathways during chlorophyll formation. HPLC is required before MC-ICP-MS can be utilized, but HPLC lacks a method for separating chlorophylls. Therefore, it is necessary to develop a set of methods for separating plant chlorophyll a and chlorophyll b. The samples separated by this method are suitable for magnesium isotope determination by MC-ICP-MS. Based on the detection wavelength of 665nm and C18 column (7.6mm×250mm, 5μm), the HPLC conditions were optimized by three-factor and three-level orthogonal design to obtain the required parameters. The correlation coefficients of chlorophyll a and chlorophyll b standard curves in the concentration range of 5−50mg/L were greater than 0.9996, the detection limits were 0.40−1.09mg/L, the quantification limits were 1.22−3.31mg/L, the relative standard deviation was less than 8.10%, and the recoveries were 91.92%−111.11%. The magnesium isotope data of the isolated samples also showed that the column temperature of 25℃, flow rate of 1mL/min, and methanol-acetone (80∶20, V/V) mobile phase were reliable as HPLC separation conditions. The method established in this paper provides technical support for the separation of chlorophyll a and chlorophyll b in plants, and the separated samples can be used for magnesium isotope determination. The BRIEF REPORT is available for this paper at http://www.ykcs.ac.cn/en/article/doi/10.15898/j.ykcs.202208300161.http://www.ykcs.ac.cn/article/doi/10.15898/j.ykcs.202208300161magnesium isotopestandard-sample-bracketing methodhigh performance liquid chromatographymobile phasechlorophyll achlorophyll b
spellingShingle Zihan AN
Hongyu ZHANG
Jiaxin YIN
Pan ZHANG
Min YAO
Kangjun HUANG
Determination of Magnesium Isotopic Composition of Plant Chlorophylls Based on HPLC and MC-ICP-MS
Yankuang ceshi
magnesium isotope
standard-sample-bracketing method
high performance liquid chromatography
mobile phase
chlorophyll a
chlorophyll b
title Determination of Magnesium Isotopic Composition of Plant Chlorophylls Based on HPLC and MC-ICP-MS
title_full Determination of Magnesium Isotopic Composition of Plant Chlorophylls Based on HPLC and MC-ICP-MS
title_fullStr Determination of Magnesium Isotopic Composition of Plant Chlorophylls Based on HPLC and MC-ICP-MS
title_full_unstemmed Determination of Magnesium Isotopic Composition of Plant Chlorophylls Based on HPLC and MC-ICP-MS
title_short Determination of Magnesium Isotopic Composition of Plant Chlorophylls Based on HPLC and MC-ICP-MS
title_sort determination of magnesium isotopic composition of plant chlorophylls based on hplc and mc icp ms
topic magnesium isotope
standard-sample-bracketing method
high performance liquid chromatography
mobile phase
chlorophyll a
chlorophyll b
url http://www.ykcs.ac.cn/article/doi/10.15898/j.ykcs.202208300161
work_keys_str_mv AT zihanan determinationofmagnesiumisotopiccompositionofplantchlorophyllsbasedonhplcandmcicpms
AT hongyuzhang determinationofmagnesiumisotopiccompositionofplantchlorophyllsbasedonhplcandmcicpms
AT jiaxinyin determinationofmagnesiumisotopiccompositionofplantchlorophyllsbasedonhplcandmcicpms
AT panzhang determinationofmagnesiumisotopiccompositionofplantchlorophyllsbasedonhplcandmcicpms
AT minyao determinationofmagnesiumisotopiccompositionofplantchlorophyllsbasedonhplcandmcicpms
AT kangjunhuang determinationofmagnesiumisotopiccompositionofplantchlorophyllsbasedonhplcandmcicpms