Axial Length and Ocular Development of Premature Infants without ROP

Purpose. To investigate the ocular parameters of premature infants without ROP at gestational age (GA) more than 28 weeks and their relationship with growth parameters. Methods. 76 preterm infants without ROP and 65 term infants were involved to undergo portable slit lamp, RetCam3, ultrasonic A-scan...

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Main Authors: Yi Zha, Guangdong Zhu, Jinfei Zhuang, Haihua Zheng, Jianqiu Cai, Wangqiang Feng
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2017/6823965
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author Yi Zha
Guangdong Zhu
Jinfei Zhuang
Haihua Zheng
Jianqiu Cai
Wangqiang Feng
author_facet Yi Zha
Guangdong Zhu
Jinfei Zhuang
Haihua Zheng
Jianqiu Cai
Wangqiang Feng
author_sort Yi Zha
collection DOAJ
description Purpose. To investigate the ocular parameters of premature infants without ROP at gestational age (GA) more than 28 weeks and their relationship with growth parameters. Methods. 76 preterm infants without ROP and 65 term infants were involved to undergo portable slit lamp, RetCam3, ultrasonic A-scan biometry, and cycloplegic streak examination at their 40 weeks’ postconceptional ages (PCA). Ocular parameters of infants’ right eye and growth parameters were used for analysis. Results. All the infants were examined at 40 weeks’ PCA. No significant difference was found between male and female in axial length of preterm infants (p = 0.993) and term infants (p=0.591). Significant differences were found in axial length (AL), anterior chamber depth (ACD), lens thickness (LT), and vitreous depth (VD) between preterm and term infants. No significant correlation was found between AL and spherical equivalent in preterm infants’ group. In preterm group, AL was significantly correlated with gestational age (GA), birth weight (BW), and head circumference (HC). Conclusions. Preterm infants had shorter AL, shallow ACD, thicker LT, and thinner VD compared to term infants. Refractive error in preterm infants at GA between 28 to 37 weeks was not related to axial length. Among all the growth parameters of preterm infants, GA, BW, and HC had effect on axial length.
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institution Kabale University
issn 2090-004X
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publishDate 2017-01-01
publisher Wiley
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series Journal of Ophthalmology
spelling doaj-art-8365fbbf20bc4ce5a50dbffb116cc9502025-08-20T03:37:51ZengWileyJournal of Ophthalmology2090-004X2090-00582017-01-01201710.1155/2017/68239656823965Axial Length and Ocular Development of Premature Infants without ROPYi Zha0Guangdong Zhu1Jinfei Zhuang2Haihua Zheng3Jianqiu Cai4Wangqiang Feng5The 2nd Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, 109 Xueyuan Road, Wenzhou, Zhejiang 325027, ChinaThe 2nd Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, 109 Xueyuan Road, Wenzhou, Zhejiang 325027, ChinaThe 2nd Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, 109 Xueyuan Road, Wenzhou, Zhejiang 325027, ChinaThe 2nd Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, 109 Xueyuan Road, Wenzhou, Zhejiang 325027, ChinaThe 2nd Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, 109 Xueyuan Road, Wenzhou, Zhejiang 325027, ChinaThe 2nd Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, 109 Xueyuan Road, Wenzhou, Zhejiang 325027, ChinaPurpose. To investigate the ocular parameters of premature infants without ROP at gestational age (GA) more than 28 weeks and their relationship with growth parameters. Methods. 76 preterm infants without ROP and 65 term infants were involved to undergo portable slit lamp, RetCam3, ultrasonic A-scan biometry, and cycloplegic streak examination at their 40 weeks’ postconceptional ages (PCA). Ocular parameters of infants’ right eye and growth parameters were used for analysis. Results. All the infants were examined at 40 weeks’ PCA. No significant difference was found between male and female in axial length of preterm infants (p = 0.993) and term infants (p=0.591). Significant differences were found in axial length (AL), anterior chamber depth (ACD), lens thickness (LT), and vitreous depth (VD) between preterm and term infants. No significant correlation was found between AL and spherical equivalent in preterm infants’ group. In preterm group, AL was significantly correlated with gestational age (GA), birth weight (BW), and head circumference (HC). Conclusions. Preterm infants had shorter AL, shallow ACD, thicker LT, and thinner VD compared to term infants. Refractive error in preterm infants at GA between 28 to 37 weeks was not related to axial length. Among all the growth parameters of preterm infants, GA, BW, and HC had effect on axial length.http://dx.doi.org/10.1155/2017/6823965
spellingShingle Yi Zha
Guangdong Zhu
Jinfei Zhuang
Haihua Zheng
Jianqiu Cai
Wangqiang Feng
Axial Length and Ocular Development of Premature Infants without ROP
Journal of Ophthalmology
title Axial Length and Ocular Development of Premature Infants without ROP
title_full Axial Length and Ocular Development of Premature Infants without ROP
title_fullStr Axial Length and Ocular Development of Premature Infants without ROP
title_full_unstemmed Axial Length and Ocular Development of Premature Infants without ROP
title_short Axial Length and Ocular Development of Premature Infants without ROP
title_sort axial length and ocular development of premature infants without rop
url http://dx.doi.org/10.1155/2017/6823965
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AT guangdongzhu axiallengthandoculardevelopmentofprematureinfantswithoutrop
AT jinfeizhuang axiallengthandoculardevelopmentofprematureinfantswithoutrop
AT haihuazheng axiallengthandoculardevelopmentofprematureinfantswithoutrop
AT jianqiucai axiallengthandoculardevelopmentofprematureinfantswithoutrop
AT wangqiangfeng axiallengthandoculardevelopmentofprematureinfantswithoutrop