Fatal Pulmonary Tumor Embolic Microangiopathy in Young Lady without Known Primary Malignancy

Pulmonary embolism (PE) is a common cause of morbidity and mortality in hospitalized patients. Malignancy, prolonged recumbence, and chemotherapy are renowned risk factors for development of clinically significant PE. Cancer exerts a multitude of pathophysiological processes, for example, hypercoagu...

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Main Authors: Adel Hammodi, M. Ali Al-Azem, Ahmed Hanafy, Talal Nakkar
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Critical Care
Online Access:http://dx.doi.org/10.1155/2014/231081
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author Adel Hammodi
M. Ali Al-Azem
Ahmed Hanafy
Talal Nakkar
author_facet Adel Hammodi
M. Ali Al-Azem
Ahmed Hanafy
Talal Nakkar
author_sort Adel Hammodi
collection DOAJ
description Pulmonary embolism (PE) is a common cause of morbidity and mortality in hospitalized patients. Malignancy, prolonged recumbence, and chemotherapy are renowned risk factors for development of clinically significant PE. Cancer exerts a multitude of pathophysiological processes, for example, hypercoagulability and abnormal vessels with sluggish circulation that can lead to PE. One of the peculiar characteristics of tumor cells is their ability to reach the circulation and behave as blood clot—not a metastasis-occluding the pulmonary circulation. We present a case of fatal pulmonary embolism diagnosed histologically to be due to tumor cell embolism.
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institution Kabale University
issn 2090-6420
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language English
publishDate 2014-01-01
publisher Wiley
record_format Article
series Case Reports in Critical Care
spelling doaj-art-835eba2828124ffc991c3c1dffe7cf9b2025-08-20T03:37:31ZengWileyCase Reports in Critical Care2090-64202090-64392014-01-01201410.1155/2014/231081231081Fatal Pulmonary Tumor Embolic Microangiopathy in Young Lady without Known Primary MalignancyAdel Hammodi0M. Ali Al-Azem1Ahmed Hanafy2Talal Nakkar3King Fahad Specialist Hospital, P.O. Box 15215, Dammam 31444, Saudi ArabiaCritical Care Department, King Fahad Specialist Hospital, P.O. Box 15215, Dammam 31444, Saudi ArabiaKing Fahad Specialist Hospital, P.O. Box 15215, Dammam 31444, Saudi ArabiaKing Fahad Specialist Hospital, P.O. Box 15215, Dammam 31444, Saudi ArabiaPulmonary embolism (PE) is a common cause of morbidity and mortality in hospitalized patients. Malignancy, prolonged recumbence, and chemotherapy are renowned risk factors for development of clinically significant PE. Cancer exerts a multitude of pathophysiological processes, for example, hypercoagulability and abnormal vessels with sluggish circulation that can lead to PE. One of the peculiar characteristics of tumor cells is their ability to reach the circulation and behave as blood clot—not a metastasis-occluding the pulmonary circulation. We present a case of fatal pulmonary embolism diagnosed histologically to be due to tumor cell embolism.http://dx.doi.org/10.1155/2014/231081
spellingShingle Adel Hammodi
M. Ali Al-Azem
Ahmed Hanafy
Talal Nakkar
Fatal Pulmonary Tumor Embolic Microangiopathy in Young Lady without Known Primary Malignancy
Case Reports in Critical Care
title Fatal Pulmonary Tumor Embolic Microangiopathy in Young Lady without Known Primary Malignancy
title_full Fatal Pulmonary Tumor Embolic Microangiopathy in Young Lady without Known Primary Malignancy
title_fullStr Fatal Pulmonary Tumor Embolic Microangiopathy in Young Lady without Known Primary Malignancy
title_full_unstemmed Fatal Pulmonary Tumor Embolic Microangiopathy in Young Lady without Known Primary Malignancy
title_short Fatal Pulmonary Tumor Embolic Microangiopathy in Young Lady without Known Primary Malignancy
title_sort fatal pulmonary tumor embolic microangiopathy in young lady without known primary malignancy
url http://dx.doi.org/10.1155/2014/231081
work_keys_str_mv AT adelhammodi fatalpulmonarytumorembolicmicroangiopathyinyoungladywithoutknownprimarymalignancy
AT malialazem fatalpulmonarytumorembolicmicroangiopathyinyoungladywithoutknownprimarymalignancy
AT ahmedhanafy fatalpulmonarytumorembolicmicroangiopathyinyoungladywithoutknownprimarymalignancy
AT talalnakkar fatalpulmonarytumorembolicmicroangiopathyinyoungladywithoutknownprimarymalignancy