Dysregulated proliferation and immune response induced by estrogen in Egr1 knockout uterus are similar to those in immature uterus
Abstract Background A balance between estrogen (E2) and progesterone (P4) is vital for a successful pregnancy, and an imbalance between these two hormones yields female infertility. E2 mediates uterine receptivity and regulates endometrial growth, the immune system, and hormone signaling by rapidly...
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| Main Authors: | Gae Hoon Jo, Haengseok Song, Sohyun Hwang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
|
| Series: | BMC Genomics |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12864-025-11904-3 |
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