Controllable and green synthesis of cellulose nanofiber/silver nanoparticle colloids with excellent biocompatibility and antibacterial activity
The demand for antibiotic-free silver nanoparticle (AgNP) colloids is rising due to concerns over antibiotic resistance. However, conventional synthesis lacks control over AgNP size, dispersibility and stability, limiting their biomedical applications. In this study, cellulose nanofibers (CNFs) serv...
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Taylor & Francis Group
2025-12-01
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| Series: | Nanocomposites |
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| Online Access: | https://www.tandfonline.com/doi/10.1080/20550324.2025.2518753 |
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| author | Hao Gong Mengru Liu Hailong Li |
| author_facet | Hao Gong Mengru Liu Hailong Li |
| author_sort | Hao Gong |
| collection | DOAJ |
| description | The demand for antibiotic-free silver nanoparticle (AgNP) colloids is rising due to concerns over antibiotic resistance. However, conventional synthesis lacks control over AgNP size, dispersibility and stability, limiting their biomedical applications. In this study, cellulose nanofibers (CNFs) served as green reductants and dispersants to controllably synthesize CNF/AgNP colloids under UV irradiation. The process was well-described by fitting curve equations with relative standard deviations below 4.5%. The resulting colloids exhibited excellent stability, with no precipitation after 30 days and a 96.26% Ag+ reduction rate. The zeta potential remained between −61.7 and −50.3 mV, indicating strong colloidal stability. The colloids also showed outstanding biocompatibility (cell viability >100%) and strong antibacterial activity (>99.99% inhibition of E. coli and S. aureus). Long-term release studies indicated a sustained Ag+ release potential of up to 126 days. This green and controllable method offers a promising route for developing high-performance AgNP colloids for biomedical and antimicrobial applications. |
| format | Article |
| id | doaj-art-8352cd1409e24f2d81673a401a7d3f69 |
| institution | DOAJ |
| issn | 2055-0324 2055-0332 |
| language | English |
| publishDate | 2025-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Nanocomposites |
| spelling | doaj-art-8352cd1409e24f2d81673a401a7d3f692025-08-20T03:11:36ZengTaylor & Francis GroupNanocomposites2055-03242055-03322025-12-0111117318710.1080/20550324.2025.2518753Controllable and green synthesis of cellulose nanofiber/silver nanoparticle colloids with excellent biocompatibility and antibacterial activityHao Gong0Mengru Liu1Hailong Li2School of Light Industry and Engineering, South China University of Technology, Guangzhou, ChinaSchool of Light Industry and Engineering, South China University of Technology, Guangzhou, ChinaSchool of Light Industry and Engineering, South China University of Technology, Guangzhou, ChinaThe demand for antibiotic-free silver nanoparticle (AgNP) colloids is rising due to concerns over antibiotic resistance. However, conventional synthesis lacks control over AgNP size, dispersibility and stability, limiting their biomedical applications. In this study, cellulose nanofibers (CNFs) served as green reductants and dispersants to controllably synthesize CNF/AgNP colloids under UV irradiation. The process was well-described by fitting curve equations with relative standard deviations below 4.5%. The resulting colloids exhibited excellent stability, with no precipitation after 30 days and a 96.26% Ag+ reduction rate. The zeta potential remained between −61.7 and −50.3 mV, indicating strong colloidal stability. The colloids also showed outstanding biocompatibility (cell viability >100%) and strong antibacterial activity (>99.99% inhibition of E. coli and S. aureus). Long-term release studies indicated a sustained Ag+ release potential of up to 126 days. This green and controllable method offers a promising route for developing high-performance AgNP colloids for biomedical and antimicrobial applications.https://www.tandfonline.com/doi/10.1080/20550324.2025.2518753Antibacterial activitybiocompatibilityCNF/AgNP colloidscontrollable synthesis |
| spellingShingle | Hao Gong Mengru Liu Hailong Li Controllable and green synthesis of cellulose nanofiber/silver nanoparticle colloids with excellent biocompatibility and antibacterial activity Nanocomposites Antibacterial activity biocompatibility CNF/AgNP colloids controllable synthesis |
| title | Controllable and green synthesis of cellulose nanofiber/silver nanoparticle colloids with excellent biocompatibility and antibacterial activity |
| title_full | Controllable and green synthesis of cellulose nanofiber/silver nanoparticle colloids with excellent biocompatibility and antibacterial activity |
| title_fullStr | Controllable and green synthesis of cellulose nanofiber/silver nanoparticle colloids with excellent biocompatibility and antibacterial activity |
| title_full_unstemmed | Controllable and green synthesis of cellulose nanofiber/silver nanoparticle colloids with excellent biocompatibility and antibacterial activity |
| title_short | Controllable and green synthesis of cellulose nanofiber/silver nanoparticle colloids with excellent biocompatibility and antibacterial activity |
| title_sort | controllable and green synthesis of cellulose nanofiber silver nanoparticle colloids with excellent biocompatibility and antibacterial activity |
| topic | Antibacterial activity biocompatibility CNF/AgNP colloids controllable synthesis |
| url | https://www.tandfonline.com/doi/10.1080/20550324.2025.2518753 |
| work_keys_str_mv | AT haogong controllableandgreensynthesisofcellulosenanofibersilvernanoparticlecolloidswithexcellentbiocompatibilityandantibacterialactivity AT mengruliu controllableandgreensynthesisofcellulosenanofibersilvernanoparticlecolloidswithexcellentbiocompatibilityandantibacterialactivity AT hailongli controllableandgreensynthesisofcellulosenanofibersilvernanoparticlecolloidswithexcellentbiocompatibilityandantibacterialactivity |