Decellularised matrices from force loaded periodontal ligament stem cells support osteogenic differentiation

Decellularised matrices from force loaded periodontal ligament stem cells support osteogenic differentiation

Abstract Periodontal ligament stem cells (hPDLSCs) are mechanosensing cells responding to mechanical forces. This study investigates the impact of decellularised extracellular matrix (dECM) derived from intermittent compressive force (ICF)-treated hPDLSCs on osteogenic differentiation. hPDSCLs were...

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Main Authors: Suphalak Phothichailert, Chatvadee Kornsuthisopon, Ajjima Chansaenroj, Vorapat Trachoo, Nunthawan Nowwarote, Benjamin Fournier, Worachat Namangkalakul, Thanaphum Osathanon
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Decellularisation
Intermittent compressive force
Extracellular matrix
Periodontal ligament stem cells
Online Access:https://doi.org/10.1038/s41598-025-14343-y
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