CARVEDILOL EFFECTS ON INSULIN RESISTANCE AS A FACTOR DEFINING CLINICAL EFFECTIVENESS IN METABOLIC SYNDROME

In 62 patients with Stage I-II arterial hypertension (AH) and metabolic syndrome (MS), clinical effectiveness and insulin resistance (IR) effects of a non-selective alpha-beta-adrenoblocker carvetrend were investigated, for 16-week carvetrend monotherapy, carvetrend combination with corinfar UNO, or...

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Bibliographic Details
Main Authors: V. E. Oleynikov, I. B. Matrosova, I. V. Eliseeva, Yu. A. Tomashevskaya
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2009-04-01
Series:Российский кардиологический журнал
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Online Access:https://russjcardiol.elpub.ru/jour/article/view/1339
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Summary:In 62 patients with Stage I-II arterial hypertension (AH) and metabolic syndrome (MS), clinical effectiveness and insulin resistance (IR) effects of a non-selective alpha-beta-adrenoblocker carvetrend were investigated, for 16-week carvetrend monotherapy, carvetrend combination with corinfar UNO, or their combination with formin and zorstat. Carvetrend, as monotherapy or combined with corinfar UNO, effectively reduced office and 24-hour monitoring blood pressure levels, regardless of the risk factor number. Carvetrend increased peripheral tissue insulin sensitivity, without affecting carbohydrate and lipid metabolism.
ISSN:1560-4071
2618-7620