Deferred Stenting for Heavy Thrombus Burden During Percutaneous Coronary Intervention for ST-Elevation MI

Patients with ST-elevation MI (STEMI) usually have a huge thrombus burden in the infarct-related artery. Stenting may lead to high chances of the slow-flow/no-reflow phenomenon that leads to periprocedural MI and adverse cardiovascular events. Deferred stenting may be beneficial in this situation as...

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Main Authors: Akshyaya Pradhan, Monika Bhandari, Pravesh Vishwakarma, Rishi Sethi
Format: Article
Language:English
Published: Radcliffe Medical Media 2021-03-01
Series:European Cardiology Review
Online Access:https://www.ecrjournal.com/articleindex/ecr.2020.31
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author Akshyaya Pradhan
Monika Bhandari
Pravesh Vishwakarma
Rishi Sethi
author_facet Akshyaya Pradhan
Monika Bhandari
Pravesh Vishwakarma
Rishi Sethi
author_sort Akshyaya Pradhan
collection DOAJ
description Patients with ST-elevation MI (STEMI) usually have a huge thrombus burden in the infarct-related artery. Stenting may lead to high chances of the slow-flow/no-reflow phenomenon that leads to periprocedural MI and adverse cardiovascular events. Deferred stenting may be beneficial in this situation as the thrombus burden will reduce, mitigating the slow-flow/no-reflow phenomenon. However, routine deferral of stenting in patients with STEMI has not been found to be beneficial, but when the patient is properly selected, deferred stenting has the potential for reducing the final infarct size. The authors report the safety and feasibility of deferred stenting after 5 days of prolonged anticoagulation in a 45-year-old smoker with STEMI who had a large thrombus load shown on an angiogram. They review the registries, trials and meta-analyses on deferred stenting in the literature and analyse the benefits and harms of the strategy. They also propose an algorithm for applying a strategy for deferred stenting in clinical practice based on the available data.
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issn 1758-3756
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publishDate 2021-03-01
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record_format Article
series European Cardiology Review
spelling doaj-art-833dfe9d71d24cb88434992f95c3e93a2025-08-20T02:39:22ZengRadcliffe Medical MediaEuropean Cardiology Review1758-37561758-37642021-03-011610.15420/ecr.2020.31Deferred Stenting for Heavy Thrombus Burden During Percutaneous Coronary Intervention for ST-Elevation MIAkshyaya Pradhan0Monika Bhandari1Pravesh Vishwakarma2Rishi Sethi3Department of Cardiology, King George’s Medical University, Lucknow, IndiaDepartment of Cardiology, King George’s Medical University, Lucknow, IndiaDepartment of Cardiology, King George’s Medical University, Lucknow, IndiaDepartment of Cardiology, King George’s Medical University, Lucknow, IndiaPatients with ST-elevation MI (STEMI) usually have a huge thrombus burden in the infarct-related artery. Stenting may lead to high chances of the slow-flow/no-reflow phenomenon that leads to periprocedural MI and adverse cardiovascular events. Deferred stenting may be beneficial in this situation as the thrombus burden will reduce, mitigating the slow-flow/no-reflow phenomenon. However, routine deferral of stenting in patients with STEMI has not been found to be beneficial, but when the patient is properly selected, deferred stenting has the potential for reducing the final infarct size. The authors report the safety and feasibility of deferred stenting after 5 days of prolonged anticoagulation in a 45-year-old smoker with STEMI who had a large thrombus load shown on an angiogram. They review the registries, trials and meta-analyses on deferred stenting in the literature and analyse the benefits and harms of the strategy. They also propose an algorithm for applying a strategy for deferred stenting in clinical practice based on the available data.https://www.ecrjournal.com/articleindex/ecr.2020.31
spellingShingle Akshyaya Pradhan
Monika Bhandari
Pravesh Vishwakarma
Rishi Sethi
Deferred Stenting for Heavy Thrombus Burden During Percutaneous Coronary Intervention for ST-Elevation MI
European Cardiology Review
title Deferred Stenting for Heavy Thrombus Burden During Percutaneous Coronary Intervention for ST-Elevation MI
title_full Deferred Stenting for Heavy Thrombus Burden During Percutaneous Coronary Intervention for ST-Elevation MI
title_fullStr Deferred Stenting for Heavy Thrombus Burden During Percutaneous Coronary Intervention for ST-Elevation MI
title_full_unstemmed Deferred Stenting for Heavy Thrombus Burden During Percutaneous Coronary Intervention for ST-Elevation MI
title_short Deferred Stenting for Heavy Thrombus Burden During Percutaneous Coronary Intervention for ST-Elevation MI
title_sort deferred stenting for heavy thrombus burden during percutaneous coronary intervention for st elevation mi
url https://www.ecrjournal.com/articleindex/ecr.2020.31
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AT praveshvishwakarma deferredstentingforheavythrombusburdenduringpercutaneouscoronaryinterventionforstelevationmi
AT rishisethi deferredstentingforheavythrombusburdenduringpercutaneouscoronaryinterventionforstelevationmi