Tinnitus in patients with orofacial complaints

Abstract Background This study explored subjective tinnitus frequency in patients referred to an interdisciplinary orofacial pain clinic using the "web-based interdisciplinary symptom evaluation" (WISE) tool, which included a wide range of psychometric data. Our goal was to analyze the cor...

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Main Authors: Nicole Peter, Jasmine Serventi, Patrick Neff, Dominik Ettlin, Aleksandra Zumbrunn Wojczyńska, Tobias Kleinjung, Nenad Lukic
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Head & Face Medicine
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Online Access:https://doi.org/10.1186/s13005-025-00505-w
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Summary:Abstract Background This study explored subjective tinnitus frequency in patients referred to an interdisciplinary orofacial pain clinic using the "web-based interdisciplinary symptom evaluation" (WISE) tool, which included a wide range of psychometric data. Our goal was to analyze the correlation between orofacial complaints and tinnitus, as well as their association with other psychometric data—an approach that, to our knowledge, has not been undertaken to this extent before. Methods From 2017 to 2020, we analyzed 1369 anonymized patient records using completed WISE. This included diverse questionnaires and symptom-related screener questions. Positive screening responses triggered additional assessments, such as short Tinnitus Handicap Inventory (THI-12) and Patient Health Questionnaire 4 (PHQ-4). Ear symptoms, tinnitus severity and tinnitus frequency were evaluated. Furthermore, Spearman correlations were performed with other questionnaires addressing pain, anxiety, depression, health, stress and insomnia. Results Among 1369 patients with orofacial complaints, 69% were female. Notably, 19.7% (269) completed THI-12 due to severe ear symptoms; of these, 62.1% were female. Female mean THI-12 score was significantly lower (p = 0.007) with 9.3 (SD = 7.0) compared to males 11.6 (SD = 6.8). Additionally, there was a significantly different gender distribution between all patients with tinnitus and those with severe tinnitus (p = 0.032), with an increased proportion of men in the latter group. THI-12 positively correlated with all WISE questionnaires, strongest with PHQ-4 (p < 0.01). Conclusions Our study unveils a common co-occurrence of orofacial and ear complaints, particularly tinnitus. The practical implication of the observed gender differences suggests that in male patients presenting with orofacial pain, tinnitus and its associated distress should be actively addressed to initiate a multidisciplinary treatment approach. Clinical trial number Not applicable. Since this study was a retrospective analysis of anonymized data, trial registration was not necessary.
ISSN:1746-160X