Long-term programming of antigen-specific immunity from gene expression signatures in the PBMC of rhesus macaques immunized with an SIV DNA vaccine.

Long-term programming of antigen-specific immunity from gene expression signatures in the PBMC of rhesus macaques immunized with an SIV DNA vaccine.

While HIV-1-specific cellular immunity is thought to be critical for the suppression of viral replication, the correlates of protection have not yet been determined. Rhesus macaques (RM) are an important animal model for the study and development of vaccines against HIV/AIDS. Our laboratory has help...

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Main Authors: Sarah E Belisle, Jiangmei Yin, Devon J Shedlock, Anlan Dai, Jian Yan, Lauren Hirao, Michele A Kutzler, Mark G Lewis, Hanne Andersen, Simon M Lank, Julie A Karl, David H O'Connor, Amir Khan, Niranjan Sardesai, Jean Chang, Lauri Aicher, Robert E Palermo, David B Weiner, Michael G Katze, Jean Boyer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0019681&type=printable
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