Assessment of relative peripheral refraction in children with low myopia and pre-myopia using multispectral refraction topography
Abstract The purpose of this study was to assess the retinal relative peripheral refraction (RPR) in children with low myopia and pre-myopia, and investigate the differences in RPR using multispectral refraction topography (MRT). Ninety-five children were enrolled in the Department of Ophthalmology,...
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| author | Tao Li Bo Jiang Xiaodong Zhou |
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| description | Abstract The purpose of this study was to assess the retinal relative peripheral refraction (RPR) in children with low myopia and pre-myopia, and investigate the differences in RPR using multispectral refraction topography (MRT). Ninety-five children were enrolled in the Department of Ophthalmology, Jinshan Hospital affiliated to Fudan University. MRT could measure total RPR (TRPR) of the 53° range centered on macular fovea. TRPR divided into four quadrants: superior RPR (RPR-S), inferior RPR (RPR-I), temporal RPR (RPR-T) and nasal RPR (RPR-N). The MRT analysis report also showed RPR in the visual field of 15° (RPR-15), 30° (RPR-30) and 45° (RPR-45) centered on the macular fovea, respectively. RPR-(15–30), RPR-(30–45) and RPR-(15–45) were calculated. TRPR (R = − 0.264, P = 0.010), RPR-I (R = − 0.261, P = 0.011), RPR-T (R = − 0.240, P = 0.019), RPR-45 (R = − 0.211, P = 0.040), RPR-(30–45) (R = − 0.232, P = 0.023) and RPR-(15–45) (R = − 0.243, P = 0.018) were negatively correlated with spherical refraction. Spherical equivalent of low myopia group was significantly less than pre-myopia group (− 1.18 ± 0.57 D vs. 0.13 ± 0.31 D, P < 0.001) whereas axial length of low myopia group was significantly longer than pre-myopia group (24.14 ± 0.70 mm vs. 23.35 ± 0.60 mm, P < 0.001). TRPR of low myopia group and pre-myopia group was 0.52 ± 0.62 D and 0.32 ± 0.41 D, respectively, without sigficant difference (P = 0.075). All the RPRs were hyperopia in the children with low myopia and pre-myopia, except for RPR-T in pre-myopia group. RPR-I in low myopia group was significantly larger than that in pre-myopia group (0.42 ± 0.72 (95% CI 0.22, 0.62) D vs. 0.04 ± 0.67 (95% CI − 0.17, 0.25) D, P = 0.010). In conclusion, RPRs become more hyperopia with the changing trend from pre-myopia to myopia. Children with low myopia and pre-myopia have relative peripheral hyperopia. Furthermore, children with low myopia have larger relative peripheral hyperopia compared with pre-myopia. |
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| institution | Kabale University |
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| spelling | doaj-art-8326aa1f7f194bf2af39aed825e60ee42025-08-20T03:37:20ZengNature PortfolioScientific Reports2045-23222025-07-011511810.1038/s41598-025-04334-4Assessment of relative peripheral refraction in children with low myopia and pre-myopia using multispectral refraction topographyTao Li0Bo Jiang1Xiaodong Zhou2Department of Ophthalmology, Fudan University Jinshan HospitalDepartment of Ophthalmology, Fudan University Jinshan HospitalDepartment of Ophthalmology, Fudan University Jinshan HospitalAbstract The purpose of this study was to assess the retinal relative peripheral refraction (RPR) in children with low myopia and pre-myopia, and investigate the differences in RPR using multispectral refraction topography (MRT). Ninety-five children were enrolled in the Department of Ophthalmology, Jinshan Hospital affiliated to Fudan University. MRT could measure total RPR (TRPR) of the 53° range centered on macular fovea. TRPR divided into four quadrants: superior RPR (RPR-S), inferior RPR (RPR-I), temporal RPR (RPR-T) and nasal RPR (RPR-N). The MRT analysis report also showed RPR in the visual field of 15° (RPR-15), 30° (RPR-30) and 45° (RPR-45) centered on the macular fovea, respectively. RPR-(15–30), RPR-(30–45) and RPR-(15–45) were calculated. TRPR (R = − 0.264, P = 0.010), RPR-I (R = − 0.261, P = 0.011), RPR-T (R = − 0.240, P = 0.019), RPR-45 (R = − 0.211, P = 0.040), RPR-(30–45) (R = − 0.232, P = 0.023) and RPR-(15–45) (R = − 0.243, P = 0.018) were negatively correlated with spherical refraction. Spherical equivalent of low myopia group was significantly less than pre-myopia group (− 1.18 ± 0.57 D vs. 0.13 ± 0.31 D, P < 0.001) whereas axial length of low myopia group was significantly longer than pre-myopia group (24.14 ± 0.70 mm vs. 23.35 ± 0.60 mm, P < 0.001). TRPR of low myopia group and pre-myopia group was 0.52 ± 0.62 D and 0.32 ± 0.41 D, respectively, without sigficant difference (P = 0.075). All the RPRs were hyperopia in the children with low myopia and pre-myopia, except for RPR-T in pre-myopia group. RPR-I in low myopia group was significantly larger than that in pre-myopia group (0.42 ± 0.72 (95% CI 0.22, 0.62) D vs. 0.04 ± 0.67 (95% CI − 0.17, 0.25) D, P = 0.010). In conclusion, RPRs become more hyperopia with the changing trend from pre-myopia to myopia. Children with low myopia and pre-myopia have relative peripheral hyperopia. Furthermore, children with low myopia have larger relative peripheral hyperopia compared with pre-myopia.https://doi.org/10.1038/s41598-025-04334-4Relative peripheral refractionLow myopiaPre-myopiaMultispectral refraction topography |
| spellingShingle | Tao Li Bo Jiang Xiaodong Zhou Assessment of relative peripheral refraction in children with low myopia and pre-myopia using multispectral refraction topography Scientific Reports Relative peripheral refraction Low myopia Pre-myopia Multispectral refraction topography |
| title | Assessment of relative peripheral refraction in children with low myopia and pre-myopia using multispectral refraction topography |
| title_full | Assessment of relative peripheral refraction in children with low myopia and pre-myopia using multispectral refraction topography |
| title_fullStr | Assessment of relative peripheral refraction in children with low myopia and pre-myopia using multispectral refraction topography |
| title_full_unstemmed | Assessment of relative peripheral refraction in children with low myopia and pre-myopia using multispectral refraction topography |
| title_short | Assessment of relative peripheral refraction in children with low myopia and pre-myopia using multispectral refraction topography |
| title_sort | assessment of relative peripheral refraction in children with low myopia and pre myopia using multispectral refraction topography |
| topic | Relative peripheral refraction Low myopia Pre-myopia Multispectral refraction topography |
| url | https://doi.org/10.1038/s41598-025-04334-4 |
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