A retrospective cohort study comparing perioperative clinical outcomes and radiographic results between patients undergoing TLIF and OLIF surgeries

Abstract Purpose To investigate the perioperative outcomes, clinical manifestations, and radiographic indicators in patients who underwent oblique lateral lumbar fusion (OLIF) and posterior instrumentation, compared with those who underwent posterior transforaminal lumbar interbody fusion (TLIF) and...

Full description

Saved in:
Bibliographic Details
Main Authors: Qingyang Huang, Weiguo Zhu, Peng Cui, Shuaikang Wang, Di Han, Peng Wang, Shibao Lu
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Surgery
Subjects:
Online Access:https://doi.org/10.1186/s12893-025-02920-x
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850280147260801024
author Qingyang Huang
Weiguo Zhu
Peng Cui
Shuaikang Wang
Di Han
Peng Wang
Shibao Lu
author_facet Qingyang Huang
Weiguo Zhu
Peng Cui
Shuaikang Wang
Di Han
Peng Wang
Shibao Lu
author_sort Qingyang Huang
collection DOAJ
description Abstract Purpose To investigate the perioperative outcomes, clinical manifestations, and radiographic indicators in patients who underwent oblique lateral lumbar fusion (OLIF) and posterior instrumentation, compared with those who underwent posterior transforaminal lumbar interbody fusion (TLIF) and instrumentation. Methods In this retrospective cohort analysis, elderly patients diagnosed with L4-5 lumbar spinal stenosis between July 2022 and July 2023 at our institution who underwent OLIF and posterior instrumentation (OLIF group), compared with those who underwent posterior TLIF and instrumentation (TLIF group). Enhanced Recovery After Surgery (ERAS) protocol was implemented for all patients. The perioperative data, patient-reported outcomes (PROs), radiographic assessments, and complications were gathered immediately after surgery and again at the 1-year follow-up. The perioperative outcomes and immediately postoperative and follow-up radiographic outcomes were compared between the two groups. Results A total of 120 patients participated in this study, with 60 patients assigned to the OLIF group and 60 to the TLIF group. With respect to outcomes, the length of stay was notably shorter in the OLIF group compared to the TLIF group (P < 0.001). Patients in the OLIF group exhibited significantly reduced postoperative drainage volume (P < 0.001), first ambulation on the postoperative day (POD) (P < 0.001), drain placement duration (P < 0.001), and urinary catheter retention (P = 0.037) compared to those in the TLIF group. Furthermore, there were statistically significant differences between the two groups in the incidence of postoperative deep venous thrombosis (DVT) (1 vs. 8, P = 0.015), urinary tract infection (2 vs. 11, P = 0.008), pulmonary infection (2 vs. 10, P = 0.015), and nausea and vomiting (3 vs. 11, P = 0.023). With respect to radiographic measurements, At the 1-year follow-up, the posterior disc height (PDH) and intervertebral disc angle (IDA) demonstrated statistically increase in the OLIF group. The sagittal vertical axis (SVA) was statistically decrease and Lumbosacral lordosis (LL) was statistically increase in the OLIF group. Conclusion OLIF was demonstrated to have significant advantages in terms of perioperative, clinical outcomes and radiographic parameters for L4-5 lumbar spinal stenosis for elderly patients, comapred with TLIF.
format Article
id doaj-art-83257e0660594fa89fda148b02178e42
institution OA Journals
issn 1471-2482
language English
publishDate 2025-04-01
publisher BMC
record_format Article
series BMC Surgery
spelling doaj-art-83257e0660594fa89fda148b02178e422025-08-20T01:48:52ZengBMCBMC Surgery1471-24822025-04-0125111110.1186/s12893-025-02920-xA retrospective cohort study comparing perioperative clinical outcomes and radiographic results between patients undergoing TLIF and OLIF surgeriesQingyang Huang0Weiguo Zhu1Peng Cui2Shuaikang Wang3Di Han4Peng Wang5Shibao Lu6Department of Orthopedics, Xuanwu Hospital, Capital Medical UniversityDepartment of Orthopedics, Xuanwu Hospital, Capital Medical UniversityDepartment of Orthopedics, Xuanwu Hospital, Capital Medical UniversityDepartment of Orthopedics, Xuanwu Hospital, Capital Medical UniversityDepartment of Orthopedics, Xuanwu Hospital, Capital Medical UniversityDepartment of Orthopedics, Xuanwu Hospital, Capital Medical UniversityDepartment of Orthopedics, Xuanwu Hospital, Capital Medical UniversityAbstract Purpose To investigate the perioperative outcomes, clinical manifestations, and radiographic indicators in patients who underwent oblique lateral lumbar fusion (OLIF) and posterior instrumentation, compared with those who underwent posterior transforaminal lumbar interbody fusion (TLIF) and instrumentation. Methods In this retrospective cohort analysis, elderly patients diagnosed with L4-5 lumbar spinal stenosis between July 2022 and July 2023 at our institution who underwent OLIF and posterior instrumentation (OLIF group), compared with those who underwent posterior TLIF and instrumentation (TLIF group). Enhanced Recovery After Surgery (ERAS) protocol was implemented for all patients. The perioperative data, patient-reported outcomes (PROs), radiographic assessments, and complications were gathered immediately after surgery and again at the 1-year follow-up. The perioperative outcomes and immediately postoperative and follow-up radiographic outcomes were compared between the two groups. Results A total of 120 patients participated in this study, with 60 patients assigned to the OLIF group and 60 to the TLIF group. With respect to outcomes, the length of stay was notably shorter in the OLIF group compared to the TLIF group (P < 0.001). Patients in the OLIF group exhibited significantly reduced postoperative drainage volume (P < 0.001), first ambulation on the postoperative day (POD) (P < 0.001), drain placement duration (P < 0.001), and urinary catheter retention (P = 0.037) compared to those in the TLIF group. Furthermore, there were statistically significant differences between the two groups in the incidence of postoperative deep venous thrombosis (DVT) (1 vs. 8, P = 0.015), urinary tract infection (2 vs. 11, P = 0.008), pulmonary infection (2 vs. 10, P = 0.015), and nausea and vomiting (3 vs. 11, P = 0.023). With respect to radiographic measurements, At the 1-year follow-up, the posterior disc height (PDH) and intervertebral disc angle (IDA) demonstrated statistically increase in the OLIF group. The sagittal vertical axis (SVA) was statistically decrease and Lumbosacral lordosis (LL) was statistically increase in the OLIF group. Conclusion OLIF was demonstrated to have significant advantages in terms of perioperative, clinical outcomes and radiographic parameters for L4-5 lumbar spinal stenosis for elderly patients, comapred with TLIF.https://doi.org/10.1186/s12893-025-02920-xERASOblique lateral lumbar fusionTransforaminal lumbar interbody fusionPerioperative outcomesLocal intervertebral disc parameters
spellingShingle Qingyang Huang
Weiguo Zhu
Peng Cui
Shuaikang Wang
Di Han
Peng Wang
Shibao Lu
A retrospective cohort study comparing perioperative clinical outcomes and radiographic results between patients undergoing TLIF and OLIF surgeries
BMC Surgery
ERAS
Oblique lateral lumbar fusion
Transforaminal lumbar interbody fusion
Perioperative outcomes
Local intervertebral disc parameters
title A retrospective cohort study comparing perioperative clinical outcomes and radiographic results between patients undergoing TLIF and OLIF surgeries
title_full A retrospective cohort study comparing perioperative clinical outcomes and radiographic results between patients undergoing TLIF and OLIF surgeries
title_fullStr A retrospective cohort study comparing perioperative clinical outcomes and radiographic results between patients undergoing TLIF and OLIF surgeries
title_full_unstemmed A retrospective cohort study comparing perioperative clinical outcomes and radiographic results between patients undergoing TLIF and OLIF surgeries
title_short A retrospective cohort study comparing perioperative clinical outcomes and radiographic results between patients undergoing TLIF and OLIF surgeries
title_sort retrospective cohort study comparing perioperative clinical outcomes and radiographic results between patients undergoing tlif and olif surgeries
topic ERAS
Oblique lateral lumbar fusion
Transforaminal lumbar interbody fusion
Perioperative outcomes
Local intervertebral disc parameters
url https://doi.org/10.1186/s12893-025-02920-x
work_keys_str_mv AT qingyanghuang aretrospectivecohortstudycomparingperioperativeclinicaloutcomesandradiographicresultsbetweenpatientsundergoingtlifandolifsurgeries
AT weiguozhu aretrospectivecohortstudycomparingperioperativeclinicaloutcomesandradiographicresultsbetweenpatientsundergoingtlifandolifsurgeries
AT pengcui aretrospectivecohortstudycomparingperioperativeclinicaloutcomesandradiographicresultsbetweenpatientsundergoingtlifandolifsurgeries
AT shuaikangwang aretrospectivecohortstudycomparingperioperativeclinicaloutcomesandradiographicresultsbetweenpatientsundergoingtlifandolifsurgeries
AT dihan aretrospectivecohortstudycomparingperioperativeclinicaloutcomesandradiographicresultsbetweenpatientsundergoingtlifandolifsurgeries
AT pengwang aretrospectivecohortstudycomparingperioperativeclinicaloutcomesandradiographicresultsbetweenpatientsundergoingtlifandolifsurgeries
AT shibaolu aretrospectivecohortstudycomparingperioperativeclinicaloutcomesandradiographicresultsbetweenpatientsundergoingtlifandolifsurgeries
AT qingyanghuang retrospectivecohortstudycomparingperioperativeclinicaloutcomesandradiographicresultsbetweenpatientsundergoingtlifandolifsurgeries
AT weiguozhu retrospectivecohortstudycomparingperioperativeclinicaloutcomesandradiographicresultsbetweenpatientsundergoingtlifandolifsurgeries
AT pengcui retrospectivecohortstudycomparingperioperativeclinicaloutcomesandradiographicresultsbetweenpatientsundergoingtlifandolifsurgeries
AT shuaikangwang retrospectivecohortstudycomparingperioperativeclinicaloutcomesandradiographicresultsbetweenpatientsundergoingtlifandolifsurgeries
AT dihan retrospectivecohortstudycomparingperioperativeclinicaloutcomesandradiographicresultsbetweenpatientsundergoingtlifandolifsurgeries
AT pengwang retrospectivecohortstudycomparingperioperativeclinicaloutcomesandradiographicresultsbetweenpatientsundergoingtlifandolifsurgeries
AT shibaolu retrospectivecohortstudycomparingperioperativeclinicaloutcomesandradiographicresultsbetweenpatientsundergoingtlifandolifsurgeries