Challenges in diagnosing and treating ossifying fibroma in adolescent patients - a case report and review of literature
Abstract Background Ossifying fibroma (OF) is a non-common benign fibrous-osseous lesion with highly aggressive behavior and tends to recur. Here, we report a case where Ossifying Fibroma (OF) was diagnosed in an adolescent female patient and was treated by marginal mandibular resection to avoid est...
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2025-03-01
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| Online Access: | https://doi.org/10.1186/s12903-025-05547-9 |
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| author | Martín Alberto Sánchez Varela R. Pablo Romero R. Sofia Escobar V. Araceli Chamorro Constanza Martínez-Cardozo |
| author_facet | Martín Alberto Sánchez Varela R. Pablo Romero R. Sofia Escobar V. Araceli Chamorro Constanza Martínez-Cardozo |
| author_sort | Martín Alberto Sánchez Varela |
| collection | DOAJ |
| description | Abstract Background Ossifying fibroma (OF) is a non-common benign fibrous-osseous lesion with highly aggressive behavior and tends to recur. Here, we report a case where Ossifying Fibroma (OF) was diagnosed in an adolescent female patient and was treated by marginal mandibular resection to avoid esthetic and functional defects in the future. Case presentation OF was diagnosed in a 13-year-old woman incidentally. Cone-Beam Computed Tomography (CBCT) examination showed a hypodense lesion compromising the vestibular table and 34 and 35 teeth. An incisional biopsy was performed to determine the histopathological diagnosis. After a multidisciplinary consensus, tooth extraction and surgical resection of the lesion were done. In the same way, bone reconstruction using the Khoury technique with an autologous graft of an external oblique line and with a mixture of autogenous and allogenic bone and fixation screws. Clinical and imaging follow-ups after 1, 4, 15, and 23 months were included, evidencing integration of the grafts in the treated zone. Conclusions OF early identification and treatment are essential to minimize risks of losing tissues in young people. Also, to avoid negative consequences in the people´s quality of life associated with bone and teeth loss. This highlights the importance of radiographic surveillance, analyses, and interdisciplinary collaboration to optimize clinical outcomes in patients with similar conditions. |
| format | Article |
| id | doaj-art-8322cc8375584856a524b47389dbc9a7 |
| institution | DOAJ |
| issn | 1472-6831 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Oral Health |
| spelling | doaj-art-8322cc8375584856a524b47389dbc9a72025-08-20T02:54:36ZengBMCBMC Oral Health1472-68312025-03-012511810.1186/s12903-025-05547-9Challenges in diagnosing and treating ossifying fibroma in adolescent patients - a case report and review of literatureMartín Alberto Sánchez Varela0R. Pablo Romero1R. Sofia Escobar2V. Araceli Chamorro3Constanza Martínez-Cardozo4Department of Diagnosis and Surgical Sciences, Faculty of Dentistry, Universidad de Los AndesDepartment of Diagnosis and Surgical Sciences, Faculty of Dentistry, Universidad de Los AndesDental Surgeon, Universidad de Los AndesDental Surgeon, Universidad de Los AndesDepartment of Biomedical Sciences, Ethics, Research and Education, Faculty of Dentistry and Center for Biomedical Research and Innovation (CIIB), Universidad de Los AndesAbstract Background Ossifying fibroma (OF) is a non-common benign fibrous-osseous lesion with highly aggressive behavior and tends to recur. Here, we report a case where Ossifying Fibroma (OF) was diagnosed in an adolescent female patient and was treated by marginal mandibular resection to avoid esthetic and functional defects in the future. Case presentation OF was diagnosed in a 13-year-old woman incidentally. Cone-Beam Computed Tomography (CBCT) examination showed a hypodense lesion compromising the vestibular table and 34 and 35 teeth. An incisional biopsy was performed to determine the histopathological diagnosis. After a multidisciplinary consensus, tooth extraction and surgical resection of the lesion were done. In the same way, bone reconstruction using the Khoury technique with an autologous graft of an external oblique line and with a mixture of autogenous and allogenic bone and fixation screws. Clinical and imaging follow-ups after 1, 4, 15, and 23 months were included, evidencing integration of the grafts in the treated zone. Conclusions OF early identification and treatment are essential to minimize risks of losing tissues in young people. Also, to avoid negative consequences in the people´s quality of life associated with bone and teeth loss. This highlights the importance of radiographic surveillance, analyses, and interdisciplinary collaboration to optimize clinical outcomes in patients with similar conditions.https://doi.org/10.1186/s12903-025-05547-9FibromaOssifyingAlveolar ridge augmentationIncidental findingBone transplantation |
| spellingShingle | Martín Alberto Sánchez Varela R. Pablo Romero R. Sofia Escobar V. Araceli Chamorro Constanza Martínez-Cardozo Challenges in diagnosing and treating ossifying fibroma in adolescent patients - a case report and review of literature BMC Oral Health Fibroma Ossifying Alveolar ridge augmentation Incidental finding Bone transplantation |
| title | Challenges in diagnosing and treating ossifying fibroma in adolescent patients - a case report and review of literature |
| title_full | Challenges in diagnosing and treating ossifying fibroma in adolescent patients - a case report and review of literature |
| title_fullStr | Challenges in diagnosing and treating ossifying fibroma in adolescent patients - a case report and review of literature |
| title_full_unstemmed | Challenges in diagnosing and treating ossifying fibroma in adolescent patients - a case report and review of literature |
| title_short | Challenges in diagnosing and treating ossifying fibroma in adolescent patients - a case report and review of literature |
| title_sort | challenges in diagnosing and treating ossifying fibroma in adolescent patients a case report and review of literature |
| topic | Fibroma Ossifying Alveolar ridge augmentation Incidental finding Bone transplantation |
| url | https://doi.org/10.1186/s12903-025-05547-9 |
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