Therapeutic challenges in a case of psoriasis with nail onset

Nail psoriasis affects a large number of patients with psoriasis and has a major psychosocial impact. Furthermore, it may be regarded as a predictor of more severe forms of psoriasis and early sign of psoriatic arthritis. The clinical presentations vary depending on the structure affected (nail matr...

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Main Authors: Mădălina I. Mitran, Cristina I. Mitran, Maria I. Sârbu, Vasile Benea, Mircea Tampa, Simona R. Georgescu
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Journal of Mind and Medical Sciences
Subjects:
Online Access:http://scholar.valpo.edu/cgi/viewcontent.cgi?article=1084&context=jmms
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author Mădălina I. Mitran
Cristina I. Mitran
Maria I. Sârbu
Vasile Benea
Mircea Tampa
Simona R. Georgescu
author_facet Mădălina I. Mitran
Cristina I. Mitran
Maria I. Sârbu
Vasile Benea
Mircea Tampa
Simona R. Georgescu
author_sort Mădălina I. Mitran
collection DOAJ
description Nail psoriasis affects a large number of patients with psoriasis and has a major psychosocial impact. Furthermore, it may be regarded as a predictor of more severe forms of psoriasis and early sign of psoriatic arthritis. The clinical presentations vary depending on the structure affected (nail matrix or nail bed), the nail lesions may range from minor to severe, but they are not specific. Treatment is a challenge, in most cases the lesions being resistant to therapy. We present a rare case of psoriasis with nail onset in a 59-year-old woman. The nail involvement confined to the fingernails was severe, with significant impairment of the patient’s quality of life. Conventional therapies failed to improve the nail lesions, but a marked improvement was achieved under etanercept therapy
format Article
id doaj-art-8322ba099b434f5d90f3b1114ef49ebf
institution OA Journals
issn 2392-7674
language English
publishDate 2017-10-01
publisher MDPI AG
record_format Article
series Journal of Mind and Medical Sciences
spelling doaj-art-8322ba099b434f5d90f3b1114ef49ebf2025-08-20T01:55:42ZengMDPI AGJournal of Mind and Medical Sciences2392-76742017-10-014218619210.22543/7674.42.P186192Therapeutic challenges in a case of psoriasis with nail onsetMădălina I. Mitran0Cristina I. Mitran1Maria I. Sârbu2Vasile Benea3Mircea Tampa4Simona R. Georgescu5Carol Davila University, Department of Microbiology, Bucharest, Romania, Victor Babes Hospital for Infectious and Tropical Diseases, Bucharest, RomaniaCarol Davila University, Department of Microbiology, Bucharest, Romania, Victor Babes Hospital for Infectious and Tropical Diseases, Bucharest, RomaniaCarol Davila University, Department of Dermatology, Bucharest, RomaniaVictor Babes Hospital for Infectious and Tropical Diseases, Bucharest, RomaniaCarol Davila University, Department of Dermatology, Bucharest, RomaniaCarol Davila University, Department of Dermatology, Bucharest, RomaniaNail psoriasis affects a large number of patients with psoriasis and has a major psychosocial impact. Furthermore, it may be regarded as a predictor of more severe forms of psoriasis and early sign of psoriatic arthritis. The clinical presentations vary depending on the structure affected (nail matrix or nail bed), the nail lesions may range from minor to severe, but they are not specific. Treatment is a challenge, in most cases the lesions being resistant to therapy. We present a rare case of psoriasis with nail onset in a 59-year-old woman. The nail involvement confined to the fingernails was severe, with significant impairment of the patient’s quality of life. Conventional therapies failed to improve the nail lesions, but a marked improvement was achieved under etanercept therapyhttp://scholar.valpo.edu/cgi/viewcontent.cgi?article=1084&context=jmmsnail psoriasistreatmentquality of life
spellingShingle Mădălina I. Mitran
Cristina I. Mitran
Maria I. Sârbu
Vasile Benea
Mircea Tampa
Simona R. Georgescu
Therapeutic challenges in a case of psoriasis with nail onset
Journal of Mind and Medical Sciences
nail psoriasis
treatment
quality of life
title Therapeutic challenges in a case of psoriasis with nail onset
title_full Therapeutic challenges in a case of psoriasis with nail onset
title_fullStr Therapeutic challenges in a case of psoriasis with nail onset
title_full_unstemmed Therapeutic challenges in a case of psoriasis with nail onset
title_short Therapeutic challenges in a case of psoriasis with nail onset
title_sort therapeutic challenges in a case of psoriasis with nail onset
topic nail psoriasis
treatment
quality of life
url http://scholar.valpo.edu/cgi/viewcontent.cgi?article=1084&context=jmms
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AT mariaisarbu therapeuticchallengesinacaseofpsoriasiswithnailonset
AT vasilebenea therapeuticchallengesinacaseofpsoriasiswithnailonset
AT mirceatampa therapeuticchallengesinacaseofpsoriasiswithnailonset
AT simonargeorgescu therapeuticchallengesinacaseofpsoriasiswithnailonset