Rare histological presentation of adenomatoid odontogenic tumor: A series of three unique cases

Adenomatoid odontogenic tumor (AOT) is a benign neoplasm or hamartomatous lesion predominantly affecting females in the second decade, involving maxilla and often associated with unerupted maxillary canine, earning the epithet “two-thirds tumor”. The present case series illustrates unusual presentat...

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Main Authors: Bhanu Priya, Priya Kumar, Jeyaseelan Augustine, Rewa Malhotra, Aadithya B. Urs
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Oral Oncology Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S277290602400013X
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author Bhanu Priya
Priya Kumar
Jeyaseelan Augustine
Rewa Malhotra
Aadithya B. Urs
author_facet Bhanu Priya
Priya Kumar
Jeyaseelan Augustine
Rewa Malhotra
Aadithya B. Urs
author_sort Bhanu Priya
collection DOAJ
description Adenomatoid odontogenic tumor (AOT) is a benign neoplasm or hamartomatous lesion predominantly affecting females in the second decade, involving maxilla and often associated with unerupted maxillary canine, earning the epithet “two-thirds tumor”. The present case series illustrates unusual presentations of AOT including a peripheral AOT with calcifying epithelial odontogenic tumor-like areas (PAOT with CEOT-like areas), AOT associated with ossifying fibroma (AOT with OF) and AOT associated with cemento-osseous dysplasia (AOT with COD). To the best of our knowledge, PAOT with CEOT-like areas is not reported till date. Also, rarely AOT concomitant and contiguous with other odontogenic and non-odontogenic tumors such as odontoma, ossifying fibroma, cemento-osseous dysplasia have been reported in literature. Three cases of AOT with OF and two cases of AOT with COD have been documented in literature to date. Through this series, we add one case of each category and attempt to discuss its pathogenesis and prognosis.
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publisher Elsevier
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series Oral Oncology Reports
spelling doaj-art-831ff71fb4f4435481a1b06140b5d83b2025-08-20T02:26:54ZengElsevierOral Oncology Reports2772-90602024-03-01910016710.1016/j.oor.2024.100167Rare histological presentation of adenomatoid odontogenic tumor: A series of three unique casesBhanu Priya0Priya Kumar1Jeyaseelan Augustine2Rewa Malhotra3Aadithya B. Urs4Department of Oral & Maxillofacial Pathology, Maulana Azad Institute of Dental Sciences, BSZ Marg, New Delhi, 110002, IndiaCorresponding author.; Department of Oral & Maxillofacial Pathology, Maulana Azad Institute of Dental Sciences, BSZ Marg, New Delhi, 110002, IndiaDepartment of Oral & Maxillofacial Pathology, Maulana Azad Institute of Dental Sciences, BSZ Marg, New Delhi, 110002, IndiaDepartment of Oral & Maxillofacial Pathology, Maulana Azad Institute of Dental Sciences, BSZ Marg, New Delhi, 110002, IndiaDepartment of Oral & Maxillofacial Pathology, Maulana Azad Institute of Dental Sciences, BSZ Marg, New Delhi, 110002, IndiaAdenomatoid odontogenic tumor (AOT) is a benign neoplasm or hamartomatous lesion predominantly affecting females in the second decade, involving maxilla and often associated with unerupted maxillary canine, earning the epithet “two-thirds tumor”. The present case series illustrates unusual presentations of AOT including a peripheral AOT with calcifying epithelial odontogenic tumor-like areas (PAOT with CEOT-like areas), AOT associated with ossifying fibroma (AOT with OF) and AOT associated with cemento-osseous dysplasia (AOT with COD). To the best of our knowledge, PAOT with CEOT-like areas is not reported till date. Also, rarely AOT concomitant and contiguous with other odontogenic and non-odontogenic tumors such as odontoma, ossifying fibroma, cemento-osseous dysplasia have been reported in literature. Three cases of AOT with OF and two cases of AOT with COD have been documented in literature to date. Through this series, we add one case of each category and attempt to discuss its pathogenesis and prognosis.http://www.sciencedirect.com/science/article/pii/S277290602400013XAdenomatoid odontogenic tumorCEOT-like areaCemento-osseous dysplasiaOssifying fibroma
spellingShingle Bhanu Priya
Priya Kumar
Jeyaseelan Augustine
Rewa Malhotra
Aadithya B. Urs
Rare histological presentation of adenomatoid odontogenic tumor: A series of three unique cases
Oral Oncology Reports
Adenomatoid odontogenic tumor
CEOT-like area
Cemento-osseous dysplasia
Ossifying fibroma
title Rare histological presentation of adenomatoid odontogenic tumor: A series of three unique cases
title_full Rare histological presentation of adenomatoid odontogenic tumor: A series of three unique cases
title_fullStr Rare histological presentation of adenomatoid odontogenic tumor: A series of three unique cases
title_full_unstemmed Rare histological presentation of adenomatoid odontogenic tumor: A series of three unique cases
title_short Rare histological presentation of adenomatoid odontogenic tumor: A series of three unique cases
title_sort rare histological presentation of adenomatoid odontogenic tumor a series of three unique cases
topic Adenomatoid odontogenic tumor
CEOT-like area
Cemento-osseous dysplasia
Ossifying fibroma
url http://www.sciencedirect.com/science/article/pii/S277290602400013X
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