In vivo determination of protective antibody thresholds for SARS-CoV-2 variants using mouse models

In vivo determination of protective antibody thresholds for SARS-CoV-2 variants using mouse models

Neutralizing antibody titres have been shown to correlate with immune protection against COVID-19 and can be used to estimate vaccine effectiveness. Numerous studies have explored the relationship between neutralizing antibodies and protection. However, there remains a lack of quantitative data dire...

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Main Authors: Peilan Wei, Ruoxi Cai, Lu Zhang, Jingjun Zhang, Zhaoyong Zhang, Airu Zhu, Hai Li, Zhen Zhuang, Lan Chen, Jiantao Chen, Yuting Zhang, Xinyi Xiong, Bin Qu, Jianfen Zhuo, Tian Tang, Yuanyuan Zhang, Lei Chen, Qier Zhong, Zhiwei Lin, Xindan Xing, Fang Li, Qingtao Hu, Jun Dai, Yongxia Shi, Jingxian Zhao, Jincun Zhao, Yanqun Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Emerging Microbes and Infections
Subjects:
SARS-CoV-2
protective antibody
threshold
neutralizing titre
mouse model
in vivo
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2025.2459140
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