Knowledge domains and hotspots in corticosteroid use for cardiac surgery: a 23-Year bibliometric and visualized analysis
Abstract Background The safety and efficacy of prophylactic corticosteroid administration during the perioperative period of cardiac surgery have undergone extensive and comprehensive examination. In this study, we conducted a bibliometric analysis of publications addressing corticosteroid use in th...
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| Format: | Article |
| Language: | English |
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BMC
2025-07-01
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| Series: | Journal of Cardiothoracic Surgery |
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| Online Access: | https://doi.org/10.1186/s13019-025-03552-1 |
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| author | Wan-wan Zou Qi-kun Zhu Song Yang En-ze Bian Wei-zhong Zhuang Jian-zheng Cen Qiang Gao |
| author_facet | Wan-wan Zou Qi-kun Zhu Song Yang En-ze Bian Wei-zhong Zhuang Jian-zheng Cen Qiang Gao |
| author_sort | Wan-wan Zou |
| collection | DOAJ |
| description | Abstract Background The safety and efficacy of prophylactic corticosteroid administration during the perioperative period of cardiac surgery have undergone extensive and comprehensive examination. In this study, we conducted a bibliometric analysis of publications addressing corticosteroid use in the perioperative period of cardiac surgery, aiming to elucidate the principal research trajectories and emerging trends spanning the past 23 years. Methods We performed a search in the Web of Science Core Collection for publications related to the application of corticosteroids during the perioperative period of cardiac surgery, spanning from the year 2000 to October 30, 2023. Bibliometric analysis was conducted employing the biblioshiny package in R, VOSviewer, and CiteSpace. Results We identified 293 eligible publications concerning corticosteroid use during the perioperative period of cardiac surgery. Publication volume increased significantly in 2001 and 2014. Keyword co-occurrence analysis revealed four primary clusters: cardiopulmonary bypass, systemic inflammatory response, methylprednisolone, and dysfunction. Over recent decades, research focus has shifted from examining how prophylactic corticosteroid use attenuates postoperative inflammation to investigating its potential effects on clinical complications following cardiac surgery. Conclusions Considerable heterogeneity in inflammatory response phenotypes among individuals may lead to significant differences in the clinical effectiveness of prophylactic corticosteroid interventions. Thus, developing personalized treatment strategies should become a major focus in future research. |
| format | Article |
| id | doaj-art-8307eb3e2638452ab5be6ddd92bac253 |
| institution | DOAJ |
| issn | 1749-8090 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Cardiothoracic Surgery |
| spelling | doaj-art-8307eb3e2638452ab5be6ddd92bac2532025-08-20T03:06:05ZengBMCJournal of Cardiothoracic Surgery1749-80902025-07-0120111110.1186/s13019-025-03552-1Knowledge domains and hotspots in corticosteroid use for cardiac surgery: a 23-Year bibliometric and visualized analysisWan-wan Zou0Qi-kun Zhu1Song Yang2En-ze Bian3Wei-zhong Zhuang4Jian-zheng Cen5Qiang Gao6School of Medicine, South China University of TechnologyDepartment of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Southern Medical UniversityDepartment of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Southern Medical UniversityDepartment of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Southern Medical UniversityDepartment of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Southern Medical UniversityDepartment of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Southern Medical UniversitySchool of Medicine, South China University of TechnologyAbstract Background The safety and efficacy of prophylactic corticosteroid administration during the perioperative period of cardiac surgery have undergone extensive and comprehensive examination. In this study, we conducted a bibliometric analysis of publications addressing corticosteroid use in the perioperative period of cardiac surgery, aiming to elucidate the principal research trajectories and emerging trends spanning the past 23 years. Methods We performed a search in the Web of Science Core Collection for publications related to the application of corticosteroids during the perioperative period of cardiac surgery, spanning from the year 2000 to October 30, 2023. Bibliometric analysis was conducted employing the biblioshiny package in R, VOSviewer, and CiteSpace. Results We identified 293 eligible publications concerning corticosteroid use during the perioperative period of cardiac surgery. Publication volume increased significantly in 2001 and 2014. Keyword co-occurrence analysis revealed four primary clusters: cardiopulmonary bypass, systemic inflammatory response, methylprednisolone, and dysfunction. Over recent decades, research focus has shifted from examining how prophylactic corticosteroid use attenuates postoperative inflammation to investigating its potential effects on clinical complications following cardiac surgery. Conclusions Considerable heterogeneity in inflammatory response phenotypes among individuals may lead to significant differences in the clinical effectiveness of prophylactic corticosteroid interventions. Thus, developing personalized treatment strategies should become a major focus in future research.https://doi.org/10.1186/s13019-025-03552-1BibliometricCiteSpaceVOSviewerCorticosteroidsCardiac surgery |
| spellingShingle | Wan-wan Zou Qi-kun Zhu Song Yang En-ze Bian Wei-zhong Zhuang Jian-zheng Cen Qiang Gao Knowledge domains and hotspots in corticosteroid use for cardiac surgery: a 23-Year bibliometric and visualized analysis Journal of Cardiothoracic Surgery Bibliometric CiteSpace VOSviewer Corticosteroids Cardiac surgery |
| title | Knowledge domains and hotspots in corticosteroid use for cardiac surgery: a 23-Year bibliometric and visualized analysis |
| title_full | Knowledge domains and hotspots in corticosteroid use for cardiac surgery: a 23-Year bibliometric and visualized analysis |
| title_fullStr | Knowledge domains and hotspots in corticosteroid use for cardiac surgery: a 23-Year bibliometric and visualized analysis |
| title_full_unstemmed | Knowledge domains and hotspots in corticosteroid use for cardiac surgery: a 23-Year bibliometric and visualized analysis |
| title_short | Knowledge domains and hotspots in corticosteroid use for cardiac surgery: a 23-Year bibliometric and visualized analysis |
| title_sort | knowledge domains and hotspots in corticosteroid use for cardiac surgery a 23 year bibliometric and visualized analysis |
| topic | Bibliometric CiteSpace VOSviewer Corticosteroids Cardiac surgery |
| url | https://doi.org/10.1186/s13019-025-03552-1 |
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