The tryptophan-aspartate (WD) repeat domain of bovine Coronin-1A promotes mycobacterial survival by inhibiting calcium signaling-mediated phagosome-lysosome fusion

The tryptophan-aspartate (WD) repeat domain of bovine Coronin-1A promotes mycobacterial survival by inhibiting calcium signaling-mediated phagosome-lysosome fusion

Abstract Bovine tuberculosis is a chronic consumptive zoonosis, causing significant economic losses and critical public health risks. Coronin-1A is a host cytoskeleton-associated protein that is crucial for understanding the inhibition of phagosome-lysosome fusion by Mycobacterium tuberculosis (M.tb...

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Bibliographic Details
Main Authors: Jing Yang, Zhunan Li, Aicong Li, Yayi Liu, Xinyan Zhang, Yong Zhang, Yuanpeng Gao
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Veterinary Research
Subjects:
Mycobacterium tuberculosis
bovine Coronin-1A
WD repeat domain
phagosome-lysosome fusion
Online Access:https://doi.org/10.1186/s13567-025-01471-6
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