An SNP-dependent cancer-testis antigenic epitope serves as a promising immunotherapeutic target for cancer

An SNP-dependent cancer-testis antigenic epitope serves as a promising immunotherapeutic target for cancer

T cells recognize peptides presented by human leukocyte antigen molecules on the cell surface, enabling the immune surveillance of pathological conditions such as cancer. Cancer-testis (CT) antigens are promising targets for cancer immunotherapy because of their restricted expression in normal tissu...

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Bibliographic Details
Main Authors: Kenji Murata, Tomoyuki Minowa, Tomohide Tsukahara, Taku Yoshida, Akiko Minami, Munehide Nakatsugawa, Yuka Mizue, Aiko Murai, Serina Tokita, Kenta Sasaki, Hisashi Uhara, Terufumi Kubo, Takayuki Kanaseki, Toshihiko Torigoe, Yoshihiko Hirohashi
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:OncoImmunology
Subjects:
Antigenic epitope
cancer-testis antigen
cDNA expression cloning
single nucleotide polymorphism
tumor-infiltrating lymphocytes
Online Access:https://www.tandfonline.com/doi/10.1080/2162402X.2025.2528110
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