Design and Characterisation of Personal Hygiene Gels Containing a <i>Gypsophila Trichotoma</i> Extract and <i>Xanthium Strumarium</i> Essential Oil
The aim was to develop a series of handwashing gels containing a standardised extract of the aerial part of <i>Gypsophila trichotoma</i> as well as an essential oil from <i>Xanthium strumarium</i> fruits. The saponins present in the extract are a suitable alternative to synth...
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MDPI AG
2025-03-01
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| Series: | Cosmetics |
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| Online Access: | https://www.mdpi.com/2079-9284/12/2/65 |
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| author | Aleksandar Shkondrov Denitsa Momekova Maya Margaritova Zaharieva Hristo Najdenski Ekaterina Kozuharova Ilina Krasteva |
| author_facet | Aleksandar Shkondrov Denitsa Momekova Maya Margaritova Zaharieva Hristo Najdenski Ekaterina Kozuharova Ilina Krasteva |
| author_sort | Aleksandar Shkondrov |
| collection | DOAJ |
| description | The aim was to develop a series of handwashing gels containing a standardised extract of the aerial part of <i>Gypsophila trichotoma</i> as well as an essential oil from <i>Xanthium strumarium</i> fruits. The saponins present in the extract are a suitable alternative to synthetic sulphate surfactants and have better skin tolerance, and with the addition of essential oil, a higher antibacterial activity of the gels thus developed is achieved. The elaborated gels were characterised by good spreadability and a pH close to the physiological for healthy skin (pH 5.5), which is a prerequisite for improved skin tolerability. The dynamic rheological studies showed that the extract fraction increase was not associated with gel viscosity change, and it was only a function of the gelling agent concentration. The gels’ foam-forming ability increased with the increasing extract concentrations. The comparative evaluation of the antibacterial activity of elaborated gels vs. plain gel based on coco glucoside against a panel of selected pathogens demonstrated that the newly developed formulations have superior antibacterial effects. Based on the good technological characteristics and the results of antimicrobial testing of the washing gels thus developed, it can be concluded that they are promising candidates as personal hygiene products. |
| format | Article |
| id | doaj-art-82e98e49fdf84b81b67cb95d4c73c38c |
| institution | OA Journals |
| issn | 2079-9284 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cosmetics |
| spelling | doaj-art-82e98e49fdf84b81b67cb95d4c73c38c2025-08-20T02:28:20ZengMDPI AGCosmetics2079-92842025-03-011226510.3390/cosmetics12020065Design and Characterisation of Personal Hygiene Gels Containing a <i>Gypsophila Trichotoma</i> Extract and <i>Xanthium Strumarium</i> Essential OilAleksandar Shkondrov0Denitsa Momekova1Maya Margaritova Zaharieva2Hristo Najdenski3Ekaterina Kozuharova4Ilina Krasteva5Department of Pharmacognosy, Faculty of Pharmacy, Medical University of Sofia, 2 Dunav st., 1000 Sofia, BulgariaDepartment of Pharmaceutical Technology and Biopharmaceutics, Faculty of Pharmacy, Medical University of Sofia, 2 Dunav st., 1000 Sofia, BulgariaThe Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Acad. G. Bontchev st., 1113 Sofia, BulgariaThe Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Acad. G. Bontchev st., 1113 Sofia, BulgariaDepartment of Pharmacognosy, Faculty of Pharmacy, Medical University of Sofia, 2 Dunav st., 1000 Sofia, BulgariaDepartment of Pharmacognosy, Faculty of Pharmacy, Medical University of Sofia, 2 Dunav st., 1000 Sofia, BulgariaThe aim was to develop a series of handwashing gels containing a standardised extract of the aerial part of <i>Gypsophila trichotoma</i> as well as an essential oil from <i>Xanthium strumarium</i> fruits. The saponins present in the extract are a suitable alternative to synthetic sulphate surfactants and have better skin tolerance, and with the addition of essential oil, a higher antibacterial activity of the gels thus developed is achieved. The elaborated gels were characterised by good spreadability and a pH close to the physiological for healthy skin (pH 5.5), which is a prerequisite for improved skin tolerability. The dynamic rheological studies showed that the extract fraction increase was not associated with gel viscosity change, and it was only a function of the gelling agent concentration. The gels’ foam-forming ability increased with the increasing extract concentrations. The comparative evaluation of the antibacterial activity of elaborated gels vs. plain gel based on coco glucoside against a panel of selected pathogens demonstrated that the newly developed formulations have superior antibacterial effects. Based on the good technological characteristics and the results of antimicrobial testing of the washing gels thus developed, it can be concluded that they are promising candidates as personal hygiene products.https://www.mdpi.com/2079-9284/12/2/65gelwashinghygieneplant extractsaponinsessential oil |
| spellingShingle | Aleksandar Shkondrov Denitsa Momekova Maya Margaritova Zaharieva Hristo Najdenski Ekaterina Kozuharova Ilina Krasteva Design and Characterisation of Personal Hygiene Gels Containing a <i>Gypsophila Trichotoma</i> Extract and <i>Xanthium Strumarium</i> Essential Oil Cosmetics gel washing hygiene plant extract saponins essential oil |
| title | Design and Characterisation of Personal Hygiene Gels Containing a <i>Gypsophila Trichotoma</i> Extract and <i>Xanthium Strumarium</i> Essential Oil |
| title_full | Design and Characterisation of Personal Hygiene Gels Containing a <i>Gypsophila Trichotoma</i> Extract and <i>Xanthium Strumarium</i> Essential Oil |
| title_fullStr | Design and Characterisation of Personal Hygiene Gels Containing a <i>Gypsophila Trichotoma</i> Extract and <i>Xanthium Strumarium</i> Essential Oil |
| title_full_unstemmed | Design and Characterisation of Personal Hygiene Gels Containing a <i>Gypsophila Trichotoma</i> Extract and <i>Xanthium Strumarium</i> Essential Oil |
| title_short | Design and Characterisation of Personal Hygiene Gels Containing a <i>Gypsophila Trichotoma</i> Extract and <i>Xanthium Strumarium</i> Essential Oil |
| title_sort | design and characterisation of personal hygiene gels containing a i gypsophila trichotoma i extract and i xanthium strumarium i essential oil |
| topic | gel washing hygiene plant extract saponins essential oil |
| url | https://www.mdpi.com/2079-9284/12/2/65 |
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