A refined model of claudin-15 tight junction paracellular architecture by molecular dynamics simulations.
Tight-junctions between epithelial cells of biological barriers are specialized molecular structures that regulate the flux of solutes across the barrier, parallel to cell walls. The tight-junction backbone is made of strands of transmembrane proteins from the claudin family, but the molecular mecha...
Saved in:
| Main Authors: | Giulio Alberini, Fabio Benfenati, Luca Maragliano |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2017-01-01
|
| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0184190&type=printable |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Tight junctional protein family, Claudins in cancer and cancer metastasis
by: Wenxiao Ji, et al.
Published: (2025-07-01) -
Expression of Tight Junction Protein Claudin-1 in Human Crescentic Glomerulonephritis
by: Ryo Koda, et al.
Published: (2014-01-01) -
ARHGAP12 suppresses F-actin assembly to control epithelial tight junction mechanics and paracellular leak pathway permeability
by: Hana Maldivita Tambrin, et al.
Published: (2025-04-01) -
Hypoxia disrupts human bronchial epithelial barrier integrity via tight junction protein remodeling and enhanced paracellular leakage
by: Jianmin Huang, et al.
Published: (2025-08-01) -
Rho-ROCK liberates sequestered claudin for rapid de novo tight junction formation
by: Yuma Cho, et al.
Published: (2025-07-01)