Acute Inflammatory Demyelinating Polyneuropathy and a Unilateral Babinski/Plantar Reflex
Acquired acute demyelinating peripheral polyneuropathy (AADP) is a general classification of pathologies that could affect secondary the peripheral nervous system. They are characterized by an autoimmune process directed towards myelin. Clinically they are characterized by progressive weakness and m...
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| Format: | Article |
| Language: | English |
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Wiley
2008-01-01
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| Series: | Anesthesiology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2008/134958 |
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| author | Davide Cattano Brian O'connor Ra'ad Shakir Francesco Giunta Mark Palazzo |
| author_facet | Davide Cattano Brian O'connor Ra'ad Shakir Francesco Giunta Mark Palazzo |
| author_sort | Davide Cattano |
| collection | DOAJ |
| description | Acquired acute demyelinating peripheral polyneuropathy (AADP) is a general classification of pathologies that could affect secondary the peripheral nervous system. They are characterized by an autoimmune process directed towards myelin. Clinically they are characterized by progressive weakness and mild sensory changes. Acute inflammatory demyelinating polyneuropathy often is referred to as Guillain-Barré syndrome (GBS). GBS is the major cause of acute nontraumatic paralysis in healthy people and it is caused by autoimmune response to viral agents (influenza, coxsackie, Epstein-Barr virus, or cytomegalovirus) or bacterial infective organisms (Campylobacter jejuni, Mycoplasma pneumoniae). A detailed history, with symptoms of progressive usually bilateral weakness, hyporeflexia, with a typical demyelinating EMG pattern supports the diagnosis. Progressive affection of respiratory muscles and autonomic instability coupled with a protracted and unpredictable recovery normally results in the need for ICU management. We present a case report of a patient with a typical GBS presentation but with a unilateral upgoing plantar reflex (Babinski sign). A unifying diagnosis was made and based on a literature search in Pubmed appears to be the first described case of its kind. |
| format | Article |
| id | doaj-art-82dc06b12e0944f491276d87ff6bda08 |
| institution | Kabale University |
| issn | 1687-6962 1687-6970 |
| language | English |
| publishDate | 2008-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Anesthesiology Research and Practice |
| spelling | doaj-art-82dc06b12e0944f491276d87ff6bda082025-08-20T03:37:57ZengWileyAnesthesiology Research and Practice1687-69621687-69702008-01-01200810.1155/2008/134958134958Acute Inflammatory Demyelinating Polyneuropathy and a Unilateral Babinski/Plantar ReflexDavide Cattano0Brian O'connor1Ra'ad Shakir2Francesco Giunta3Mark Palazzo4Department of Surgery, University of Pisa, Pisa 56126, ItalyKings College Hospital, London SE5 9RS, UKCharing Cross Hospital, Hammersmith Hospitals NHS Trust, London W6 8RF, UKDepartment of Surgery, University of Pisa, Pisa 56126, ItalyCharing Cross Hospital, Hammersmith Hospitals NHS Trust, London W6 8RF, UKAcquired acute demyelinating peripheral polyneuropathy (AADP) is a general classification of pathologies that could affect secondary the peripheral nervous system. They are characterized by an autoimmune process directed towards myelin. Clinically they are characterized by progressive weakness and mild sensory changes. Acute inflammatory demyelinating polyneuropathy often is referred to as Guillain-Barré syndrome (GBS). GBS is the major cause of acute nontraumatic paralysis in healthy people and it is caused by autoimmune response to viral agents (influenza, coxsackie, Epstein-Barr virus, or cytomegalovirus) or bacterial infective organisms (Campylobacter jejuni, Mycoplasma pneumoniae). A detailed history, with symptoms of progressive usually bilateral weakness, hyporeflexia, with a typical demyelinating EMG pattern supports the diagnosis. Progressive affection of respiratory muscles and autonomic instability coupled with a protracted and unpredictable recovery normally results in the need for ICU management. We present a case report of a patient with a typical GBS presentation but with a unilateral upgoing plantar reflex (Babinski sign). A unifying diagnosis was made and based on a literature search in Pubmed appears to be the first described case of its kind.http://dx.doi.org/10.1155/2008/134958 |
| spellingShingle | Davide Cattano Brian O'connor Ra'ad Shakir Francesco Giunta Mark Palazzo Acute Inflammatory Demyelinating Polyneuropathy and a Unilateral Babinski/Plantar Reflex Anesthesiology Research and Practice |
| title | Acute Inflammatory Demyelinating Polyneuropathy and a Unilateral Babinski/Plantar Reflex |
| title_full | Acute Inflammatory Demyelinating Polyneuropathy and a Unilateral Babinski/Plantar Reflex |
| title_fullStr | Acute Inflammatory Demyelinating Polyneuropathy and a Unilateral Babinski/Plantar Reflex |
| title_full_unstemmed | Acute Inflammatory Demyelinating Polyneuropathy and a Unilateral Babinski/Plantar Reflex |
| title_short | Acute Inflammatory Demyelinating Polyneuropathy and a Unilateral Babinski/Plantar Reflex |
| title_sort | acute inflammatory demyelinating polyneuropathy and a unilateral babinski plantar reflex |
| url | http://dx.doi.org/10.1155/2008/134958 |
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