In-vitro acaricidal activity of peganum harmala and glaucium flavum alkaloid against rhipicephalus sp. of dog
<b>Aim: </b>The major problem of drug intended for tick control is resistance developed to application doses on the hosts. The acaricidal effects of alkaloids from Glaucium flavum and Peganum harmala were evaluated in vitro on adult female of Rhipicephalus sp. collected in naturally infe...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Selcuk University Press
2020-03-01
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| Series: | Eurasian Journal of Veterinary Sciences |
| Subjects: | |
| Online Access: | http://eurasianjvetsci.org/pdf.php3?id=1275 |
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| Summary: | <b>Aim: </b>The major problem of drug intended for tick control is resistance
developed to application doses on the hosts. The acaricidal effects
of alkaloids from Glaucium flavum and Peganum harmala were
evaluated in vitro on adult female of Rhipicephalus sp. collected in
naturally infected dogs.<p>
<b>Materials and Methods: </b>The acaricide activities of the both extracts
(3.12, 6.2, 12.5, 25 and 50 mg/ml) were evaluated using the
adult immersion test, reproductive index and inhibition oviposition.
DMSO (1%) and SEB (1?l/ml) were used as a negative and positive
control.<p>
<b>Results:</b> The percent mortality caused by the methanolic extracts
of both plants varied from 41.66 to 75 %, when tested at concentrations
ranging from 3.12 to 50 mg/ml, and significantly different
compared to control (p<0.05). Visually hatching of the eggs was
completely blocked only by G. flavum with 50 mg/ml; however, other
extracts of both plants were partially able to block the hatching. The
oviposition and reproductive rate of both plants were concentration
dependent in both plants and significantly different (p<0.05) compared
to negative control. Also, the extracts of P. harmala seem to be
more efficient against Rhipicephalus sp. adults at different concentrations
than the extracts G. flavum. The alkaloid extracts of both plants
high effects were observed with 6.25 and 50 mg/ml for G. flavum and
with 25mg/ml and 50mg/ml for P. harmala.<p>
<b>Conclusion: </b>The total alkaloids extracted from the G. flavum root
and P. harmala seed have good acaricidal activities in vitro reducing
potentially the egg laying of Rhipicephalus sp. females. |
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| ISSN: | 1309-6958 2146-1953 |