Glymphatic and neurofluidic dysfunction in classical trigeminal neuralgia: a multimodal MRI study of brain-CSF functional and structural dynamics

Glymphatic and neurofluidic dysfunction in classical trigeminal neuralgia: a multimodal MRI study of brain-CSF functional and structural dynamics

Abstract Objective To investigate whether dysfunction of the glymphatic system and altered neurofluidic dynamics contribute to the pathophysiology of classical trigeminal neuralgia (CTN), and to explore the potential interplay between brain-CSF coupling and structural brain changes. Methods A total...

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Bibliographic Details
Main Authors: Fenyang Chen, Zhiliang Zhang, Jianliang Miao, Yvting Zhang, Ding Wang, Juncheng Yan, Lei Pan, Haiqi Ye, Zhongxiang Ding, Xiuhong Ge
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Medical Imaging
Subjects:
Classical trigeminal neuralgia
Glymphatic system
Brain-CSF coupling
Choroid plexus volume
Neurofluidic dynamics
Online Access:https://doi.org/10.1186/s12880-025-01801-2
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