The Impact of Sarcopenic Obesity on Weight Loss Outcomes and Recurrent Weight Gain Following Laparoscopic Sleeve Gastrectomy
Xiaoqiang Wang,1,* Xufeng Shu,1,* Wenguang Pei,2,* Chendong Yuan,1 Xujie Su,1 Jianbo Xiong,1 Wenzheng Chen,1 Guoyang Zhang,1 Zhigang Jie,1 Yi Liu1 1Department of General Surgery, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2025-08-01
|
| Series: | Diabetes, Metabolic Syndrome and Obesity |
| Subjects: | |
| Online Access: | https://www.dovepress.com/the-impact-of-sarcopenic-obesity-on-weight-loss-outcomes-and-recurrent-peer-reviewed-fulltext-article-DMSO |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849402985514270720 |
|---|---|
| author | Wang X Shu X Pei W Yuan C Su X Xiong J Chen W Zhang G Jie Z Liu Y |
| author_facet | Wang X Shu X Pei W Yuan C Su X Xiong J Chen W Zhang G Jie Z Liu Y |
| author_sort | Wang X |
| collection | DOAJ |
| description | Xiaoqiang Wang,1,&ast; Xufeng Shu,1,&ast; Wenguang Pei,2,&ast; Chendong Yuan,1 Xujie Su,1 Jianbo Xiong,1 Wenzheng Chen,1 Guoyang Zhang,1 Zhigang Jie,1 Yi Liu1 1Department of General Surgery, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330000, People’s Republic of China; 2Department of Abdominal Tumor Surgery, Jiangxi Cancer Hospital, Nanchang, 330000, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Zhigang Jie, Email ndyfy00524@ncu.edu.cn Yi Liu, Email ndyfy01913@ncu.edu.cnBackground: Sarcopenic obesity (SO) presents a significant public health challenge. Although the prevalence of SO is on the rise, there is a notable paucity of research examining the impact of SO on weight loss efficacy following laparoscopic sleeve gastrectomy (LSG).Purpose: To investigate the impact of SO on weight loss outcomes and recurrent weight gain following LSG.Methods: We retrospectively gathered clinical data of 104 patients with obesity who underwent LSG in our hospital between January 2020 and September 2023. The ratio of fat mass to lean mass ≥ 0.8 was calculated for SO. Among them, the SO group (n=34) and the non-sarcopenic obesity (NSO) group (n=70), and the effect of SO on weight loss outcomes and recurrent weight gain were comparatively analyzed.Results: Within one year after LSG, SO patients had an apparently higher average body mass index, excess body mass index, and lower average percentage of excess weight loss than NSO patients (P< 0.05). Furthermore, NSO patients had a statistically striking optimal weight loss rate more than SO patients in the first year after surgery (58.6% vs 35.3%, P=0.026). Within two years after LSG, SO patients had a lower occurrence rate of recurrent weight gain than NSO patients. Nonetheless, this difference was not statistically significant (P=0.212). Additionally, diabetes was an independent risk factor for recurrent weight gain postoperatively in patients with obesity when both univariate and multivariate analyses were conducted (P< 0.05).Conclusion: SO adversely affects short-term weight loss outcomes after LSG. However, the effect of SO on postoperative recurrent weight gain was not statistically significant, indicating that further research is needed. Furthermore, diabetes is an independent risk factor for postoperative recurrent weight gain in patients with obesity.Keywords: sarcopenic obesity, laparoscopic sleeve gastrectomy, weight loss outcomes, postoperative recurrent weight gain, risk factors |
| format | Article |
| id | doaj-art-82d7aecb0ed448ceab31bce28f4f90d2 |
| institution | Kabale University |
| issn | 1178-7007 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Diabetes, Metabolic Syndrome and Obesity |
| spelling | doaj-art-82d7aecb0ed448ceab31bce28f4f90d22025-08-20T03:37:23ZengDove Medical PressDiabetes, Metabolic Syndrome and Obesity1178-70072025-08-01Volume 18Issue 126552665105394The Impact of Sarcopenic Obesity on Weight Loss Outcomes and Recurrent Weight Gain Following Laparoscopic Sleeve GastrectomyWang X0Shu X1Pei W2Yuan C3Su X4Xiong J5Chen W6Zhang GJie Z7Liu Y8Department of General SurgeryDepartment of General SurgeryDepartment of General SurgeryDepartment of General SurgeryDepartment of General SurgeryDepartment of General SurgeryDepartment of General SurgeryDepartment of General SurgeryDepartment of General SurgeryXiaoqiang Wang,1,&ast; Xufeng Shu,1,&ast; Wenguang Pei,2,&ast; Chendong Yuan,1 Xujie Su,1 Jianbo Xiong,1 Wenzheng Chen,1 Guoyang Zhang,1 Zhigang Jie,1 Yi Liu1 1Department of General Surgery, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, 330000, People’s Republic of China; 2Department of Abdominal Tumor Surgery, Jiangxi Cancer Hospital, Nanchang, 330000, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Zhigang Jie, Email ndyfy00524@ncu.edu.cn Yi Liu, Email ndyfy01913@ncu.edu.cnBackground: Sarcopenic obesity (SO) presents a significant public health challenge. Although the prevalence of SO is on the rise, there is a notable paucity of research examining the impact of SO on weight loss efficacy following laparoscopic sleeve gastrectomy (LSG).Purpose: To investigate the impact of SO on weight loss outcomes and recurrent weight gain following LSG.Methods: We retrospectively gathered clinical data of 104 patients with obesity who underwent LSG in our hospital between January 2020 and September 2023. The ratio of fat mass to lean mass ≥ 0.8 was calculated for SO. Among them, the SO group (n=34) and the non-sarcopenic obesity (NSO) group (n=70), and the effect of SO on weight loss outcomes and recurrent weight gain were comparatively analyzed.Results: Within one year after LSG, SO patients had an apparently higher average body mass index, excess body mass index, and lower average percentage of excess weight loss than NSO patients (P< 0.05). Furthermore, NSO patients had a statistically striking optimal weight loss rate more than SO patients in the first year after surgery (58.6% vs 35.3%, P=0.026). Within two years after LSG, SO patients had a lower occurrence rate of recurrent weight gain than NSO patients. Nonetheless, this difference was not statistically significant (P=0.212). Additionally, diabetes was an independent risk factor for recurrent weight gain postoperatively in patients with obesity when both univariate and multivariate analyses were conducted (P< 0.05).Conclusion: SO adversely affects short-term weight loss outcomes after LSG. However, the effect of SO on postoperative recurrent weight gain was not statistically significant, indicating that further research is needed. Furthermore, diabetes is an independent risk factor for postoperative recurrent weight gain in patients with obesity.Keywords: sarcopenic obesity, laparoscopic sleeve gastrectomy, weight loss outcomes, postoperative recurrent weight gain, risk factorshttps://www.dovepress.com/the-impact-of-sarcopenic-obesity-on-weight-loss-outcomes-and-recurrent-peer-reviewed-fulltext-article-DMSOsarcopenic obesitylaparoscopic sleeve gastrectomyweight loss outcomespostoperative recurrent weight gainrisk factors. |
| spellingShingle | Wang X Shu X Pei W Yuan C Su X Xiong J Chen W Zhang G Jie Z Liu Y The Impact of Sarcopenic Obesity on Weight Loss Outcomes and Recurrent Weight Gain Following Laparoscopic Sleeve Gastrectomy Diabetes, Metabolic Syndrome and Obesity sarcopenic obesity laparoscopic sleeve gastrectomy weight loss outcomes postoperative recurrent weight gain risk factors. |
| title | The Impact of Sarcopenic Obesity on Weight Loss Outcomes and Recurrent Weight Gain Following Laparoscopic Sleeve Gastrectomy |
| title_full | The Impact of Sarcopenic Obesity on Weight Loss Outcomes and Recurrent Weight Gain Following Laparoscopic Sleeve Gastrectomy |
| title_fullStr | The Impact of Sarcopenic Obesity on Weight Loss Outcomes and Recurrent Weight Gain Following Laparoscopic Sleeve Gastrectomy |
| title_full_unstemmed | The Impact of Sarcopenic Obesity on Weight Loss Outcomes and Recurrent Weight Gain Following Laparoscopic Sleeve Gastrectomy |
| title_short | The Impact of Sarcopenic Obesity on Weight Loss Outcomes and Recurrent Weight Gain Following Laparoscopic Sleeve Gastrectomy |
| title_sort | impact of sarcopenic obesity on weight loss outcomes and recurrent weight gain following laparoscopic sleeve gastrectomy |
| topic | sarcopenic obesity laparoscopic sleeve gastrectomy weight loss outcomes postoperative recurrent weight gain risk factors. |
| url | https://www.dovepress.com/the-impact-of-sarcopenic-obesity-on-weight-loss-outcomes-and-recurrent-peer-reviewed-fulltext-article-DMSO |
| work_keys_str_mv | AT wangx theimpactofsarcopenicobesityonweightlossoutcomesandrecurrentweightgainfollowinglaparoscopicsleevegastrectomy AT shux theimpactofsarcopenicobesityonweightlossoutcomesandrecurrentweightgainfollowinglaparoscopicsleevegastrectomy AT peiw theimpactofsarcopenicobesityonweightlossoutcomesandrecurrentweightgainfollowinglaparoscopicsleevegastrectomy AT yuanc theimpactofsarcopenicobesityonweightlossoutcomesandrecurrentweightgainfollowinglaparoscopicsleevegastrectomy AT sux theimpactofsarcopenicobesityonweightlossoutcomesandrecurrentweightgainfollowinglaparoscopicsleevegastrectomy AT xiongj theimpactofsarcopenicobesityonweightlossoutcomesandrecurrentweightgainfollowinglaparoscopicsleevegastrectomy AT chenw theimpactofsarcopenicobesityonweightlossoutcomesandrecurrentweightgainfollowinglaparoscopicsleevegastrectomy AT zhangg theimpactofsarcopenicobesityonweightlossoutcomesandrecurrentweightgainfollowinglaparoscopicsleevegastrectomy AT jiez theimpactofsarcopenicobesityonweightlossoutcomesandrecurrentweightgainfollowinglaparoscopicsleevegastrectomy AT liuy theimpactofsarcopenicobesityonweightlossoutcomesandrecurrentweightgainfollowinglaparoscopicsleevegastrectomy AT wangx impactofsarcopenicobesityonweightlossoutcomesandrecurrentweightgainfollowinglaparoscopicsleevegastrectomy AT shux impactofsarcopenicobesityonweightlossoutcomesandrecurrentweightgainfollowinglaparoscopicsleevegastrectomy AT peiw impactofsarcopenicobesityonweightlossoutcomesandrecurrentweightgainfollowinglaparoscopicsleevegastrectomy AT yuanc impactofsarcopenicobesityonweightlossoutcomesandrecurrentweightgainfollowinglaparoscopicsleevegastrectomy AT sux impactofsarcopenicobesityonweightlossoutcomesandrecurrentweightgainfollowinglaparoscopicsleevegastrectomy AT xiongj impactofsarcopenicobesityonweightlossoutcomesandrecurrentweightgainfollowinglaparoscopicsleevegastrectomy AT chenw impactofsarcopenicobesityonweightlossoutcomesandrecurrentweightgainfollowinglaparoscopicsleevegastrectomy AT zhangg impactofsarcopenicobesityonweightlossoutcomesandrecurrentweightgainfollowinglaparoscopicsleevegastrectomy AT jiez impactofsarcopenicobesityonweightlossoutcomesandrecurrentweightgainfollowinglaparoscopicsleevegastrectomy AT liuy impactofsarcopenicobesityonweightlossoutcomesandrecurrentweightgainfollowinglaparoscopicsleevegastrectomy |