Research progress on ethanol-degrading microorganisms and their anti-alcohol products

Alcoholism is a disease resulting from excessive ethanol intake and inadequate metabolism within a short period of time. Acute alcoholism can lead to brain dysfunction and even fatality, while chronic alcoholism is closely associated with metabolic disorders such as cardiovascular and cerebrovascula...

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Main Author: CAO Jinghua, LI Tianxin, LIU Rui, ZHU Zhengjun, LI Li, WANG Jiangbo
Format: Article
Language:English
Published: Editorial Department of China Brewing 2025-04-01
Series:Zhongguo niangzao
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Online Access:https://manu61.magtech.com.cn/zgnz/fileup/0254-5071/PDF/0254-5071-2025-44-4-27.pdf
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author CAO Jinghua, LI Tianxin, LIU Rui, ZHU Zhengjun, LI Li, WANG Jiangbo
author_facet CAO Jinghua, LI Tianxin, LIU Rui, ZHU Zhengjun, LI Li, WANG Jiangbo
author_sort CAO Jinghua, LI Tianxin, LIU Rui, ZHU Zhengjun, LI Li, WANG Jiangbo
collection DOAJ
description Alcoholism is a disease resulting from excessive ethanol intake and inadequate metabolism within a short period of time. Acute alcoholism can lead to brain dysfunction and even fatality, while chronic alcoholism is closely associated with metabolic disorders such as cardiovascular and cerebrovascular diseases, as well as liver diseases. The intervention of ethanol metabolism through microorganisms presents a potentially safe, cost- effective, and efficient approach. Ethanol-degrading microorganisms have the ability to metabolize ethanol by producing enzymes and enhancing enzyme expression in the body, or they can inhibit ethanol absorption by restoring intestinal flora homeostasis, reducing intestinal permeability, and promoting antioxidant activity to mitigate alcoholic liver injury. The ways, characteristics of microbial degradation of ethanol and the function and characteristics of related anti-alcohol products were reviewed, aiming to establish a theoretical foundation for future research.
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institution OA Journals
issn 0254-5071
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publishDate 2025-04-01
publisher Editorial Department of China Brewing
record_format Article
series Zhongguo niangzao
spelling doaj-art-82d6dcb2c6e343c097da0f74e9c5e1dc2025-08-20T01:52:19ZengEditorial Department of China BrewingZhongguo niangzao0254-50712025-04-01444273210.11882/j.issn.0254-5071.2025.04.005Research progress on ethanol-degrading microorganisms and their anti-alcohol productsCAO Jinghua, LI Tianxin, LIU Rui, ZHU Zhengjun, LI Li, WANG Jiangbo01.Cooperative Innovation Center of Industrial Fermentation (Ministry of Education & Hubei Province), Key Laboratory of Fermentation Engineering (Ministry of Education), Hubei Key Laboratory of Industrial Microbiology, School of Life and Health Sciences, Hubei University of Technology, Wuhan 430068, China;;2.Hubei Lingjiaozhou Ecological Technology Co., Ltd., Wuhan 430030, ChinaAlcoholism is a disease resulting from excessive ethanol intake and inadequate metabolism within a short period of time. Acute alcoholism can lead to brain dysfunction and even fatality, while chronic alcoholism is closely associated with metabolic disorders such as cardiovascular and cerebrovascular diseases, as well as liver diseases. The intervention of ethanol metabolism through microorganisms presents a potentially safe, cost- effective, and efficient approach. Ethanol-degrading microorganisms have the ability to metabolize ethanol by producing enzymes and enhancing enzyme expression in the body, or they can inhibit ethanol absorption by restoring intestinal flora homeostasis, reducing intestinal permeability, and promoting antioxidant activity to mitigate alcoholic liver injury. The ways, characteristics of microbial degradation of ethanol and the function and characteristics of related anti-alcohol products were reviewed, aiming to establish a theoretical foundation for future research.https://manu61.magtech.com.cn/zgnz/fileup/0254-5071/PDF/0254-5071-2025-44-4-27.pdfethanol|degradation|microorganisms|anti-alcohol products|anti-alcohol mechanism
spellingShingle CAO Jinghua, LI Tianxin, LIU Rui, ZHU Zhengjun, LI Li, WANG Jiangbo
Research progress on ethanol-degrading microorganisms and their anti-alcohol products
Zhongguo niangzao
ethanol|degradation|microorganisms|anti-alcohol products|anti-alcohol mechanism
title Research progress on ethanol-degrading microorganisms and their anti-alcohol products
title_full Research progress on ethanol-degrading microorganisms and their anti-alcohol products
title_fullStr Research progress on ethanol-degrading microorganisms and their anti-alcohol products
title_full_unstemmed Research progress on ethanol-degrading microorganisms and their anti-alcohol products
title_short Research progress on ethanol-degrading microorganisms and their anti-alcohol products
title_sort research progress on ethanol degrading microorganisms and their anti alcohol products
topic ethanol|degradation|microorganisms|anti-alcohol products|anti-alcohol mechanism
url https://manu61.magtech.com.cn/zgnz/fileup/0254-5071/PDF/0254-5071-2025-44-4-27.pdf
work_keys_str_mv AT caojinghualitianxinliuruizhuzhengjunliliwangjiangbo researchprogressonethanoldegradingmicroorganismsandtheirantialcoholproducts