Chronic migraine patients show cognitive impairment in an extended neuropsychological assessment

ABSTRACT The objective of the present study was to assess the presence of cognitive deficits in patients with chronic migraine, and to assess the main factors that trigger cognitive disorders, such as comorbidities or the use of medications. Methods: Chronic migraine and control groups were intervi...

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Main Authors: Karen S. Ferreira, Caroliny T. Teixeira, Carolina Cáfaro, Gabriela Z. Oliver, Gabriela L. P. Carvalho, Larissa A. S. D. Carvalho, Brenda G. Silva, Fernanda B. B. Haes, Marcelo C. Ciciarelli
Format: Article
Language:English
Published: Thieme Revinter Publicações
Series:Arquivos de Neuro-Psiquiatria
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018000900582&lng=en&tlng=en
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author Karen S. Ferreira
Caroliny T. Teixeira
Carolina Cáfaro
Gabriela Z. Oliver
Gabriela L. P. Carvalho
Larissa A. S. D. Carvalho
Brenda G. Silva
Fernanda B. B. Haes
Marcelo C. Ciciarelli
author_facet Karen S. Ferreira
Caroliny T. Teixeira
Carolina Cáfaro
Gabriela Z. Oliver
Gabriela L. P. Carvalho
Larissa A. S. D. Carvalho
Brenda G. Silva
Fernanda B. B. Haes
Marcelo C. Ciciarelli
author_sort Karen S. Ferreira
collection DOAJ
description ABSTRACT The objective of the present study was to assess the presence of cognitive deficits in patients with chronic migraine, and to assess the main factors that trigger cognitive disorders, such as comorbidities or the use of medications. Methods: Chronic migraine and control groups were interviewed in a case-control study. The frequency and intensity of the headache, medication used and associated comorbidities were determined. All patients were submitted to an extended neuropsychological assessment. Results: The chronic migraine group (n = 30) had a worse performance in the Montreal Cognitive Assessment Test (p = 0.00), Verbal Fluency (p = 0.00), Stroop (p = 0.00), Clock Drawing Test (p = 0.00), Digit Span (p = 0.00) and Matrix Reasoning (p = 0.01). After statistical adjustment by linear regression, migraine continued to be the only relevant factor in the poorer performance in the Montreal Cognitive Assessment, Verbal Fluency, Clock Drawing and Stroop tests. Conclusion: Patients with chronic migraine have cognitive deficits in multiple tasks, regardless of the presence of comorbidities or the use of medications.
format Article
id doaj-art-82d68bbf2dad4fa88ae5cefdf6b1dc46
institution OA Journals
issn 1678-4227
language English
publisher Thieme Revinter Publicações
record_format Article
series Arquivos de Neuro-Psiquiatria
spelling doaj-art-82d68bbf2dad4fa88ae5cefdf6b1dc462025-08-20T02:08:46ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-422776958258710.1590/0004-282x20180085S0004-282X2018000900582Chronic migraine patients show cognitive impairment in an extended neuropsychological assessmentKaren S. FerreiraCaroliny T. TeixeiraCarolina CáfaroGabriela Z. OliverGabriela L. P. CarvalhoLarissa A. S. D. CarvalhoBrenda G. SilvaFernanda B. B. HaesMarcelo C. CiciarelliABSTRACT The objective of the present study was to assess the presence of cognitive deficits in patients with chronic migraine, and to assess the main factors that trigger cognitive disorders, such as comorbidities or the use of medications. Methods: Chronic migraine and control groups were interviewed in a case-control study. The frequency and intensity of the headache, medication used and associated comorbidities were determined. All patients were submitted to an extended neuropsychological assessment. Results: The chronic migraine group (n = 30) had a worse performance in the Montreal Cognitive Assessment Test (p = 0.00), Verbal Fluency (p = 0.00), Stroop (p = 0.00), Clock Drawing Test (p = 0.00), Digit Span (p = 0.00) and Matrix Reasoning (p = 0.01). After statistical adjustment by linear regression, migraine continued to be the only relevant factor in the poorer performance in the Montreal Cognitive Assessment, Verbal Fluency, Clock Drawing and Stroop tests. Conclusion: Patients with chronic migraine have cognitive deficits in multiple tasks, regardless of the presence of comorbidities or the use of medications.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018000900582&lng=en&tlng=enheadachemigraine disorderscognitive dysfunction
spellingShingle Karen S. Ferreira
Caroliny T. Teixeira
Carolina Cáfaro
Gabriela Z. Oliver
Gabriela L. P. Carvalho
Larissa A. S. D. Carvalho
Brenda G. Silva
Fernanda B. B. Haes
Marcelo C. Ciciarelli
Chronic migraine patients show cognitive impairment in an extended neuropsychological assessment
Arquivos de Neuro-Psiquiatria
headache
migraine disorders
cognitive dysfunction
title Chronic migraine patients show cognitive impairment in an extended neuropsychological assessment
title_full Chronic migraine patients show cognitive impairment in an extended neuropsychological assessment
title_fullStr Chronic migraine patients show cognitive impairment in an extended neuropsychological assessment
title_full_unstemmed Chronic migraine patients show cognitive impairment in an extended neuropsychological assessment
title_short Chronic migraine patients show cognitive impairment in an extended neuropsychological assessment
title_sort chronic migraine patients show cognitive impairment in an extended neuropsychological assessment
topic headache
migraine disorders
cognitive dysfunction
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2018000900582&lng=en&tlng=en
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