Reversal of Chorea Hyperglycemia Basal Ganglia Syndrome With Glycemic Control: A Case Report

Chorea Hyperglycemia Basal Ganglia Syndrome (CHBG) is an uncommon neurological complication arising in diabetic patients with severe, non-ketotic hyperglycemia. This case report describes a 50-year-old woman presenting with new-onset, choreiform movements in her extremities. Initial workup revealed...

Full description

Saved in:
Bibliographic Details
Main Authors: Sumanth Gundraju, Jaideep Menda, Tarun Kumar Suvvari, Anupama Kumudavalli Pindi, Prudhvi Kumar Davala, Tejinder Singh, Vimal Thomas
Format: Article
Language:English
Published: SAGE Publishing 2025-05-01
Series:Clinical Medicine Insights: Case Reports
Online Access:https://doi.org/10.1177/11795476251345877
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1849718235614674944
author Sumanth Gundraju
Jaideep Menda
Tarun Kumar Suvvari
Anupama Kumudavalli Pindi
Prudhvi Kumar Davala
Tejinder Singh
Vimal Thomas
author_facet Sumanth Gundraju
Jaideep Menda
Tarun Kumar Suvvari
Anupama Kumudavalli Pindi
Prudhvi Kumar Davala
Tejinder Singh
Vimal Thomas
author_sort Sumanth Gundraju
collection DOAJ
description Chorea Hyperglycemia Basal Ganglia Syndrome (CHBG) is an uncommon neurological complication arising in diabetic patients with severe, non-ketotic hyperglycemia. This case report describes a 50-year-old woman presenting with new-onset, choreiform movements in her extremities. Initial workup revealed uncontrolled diabetes (plasma glucose 410 mg/dl, HbA1c 11.2%) with negative serum ketones. Brain MRI findings supported the diagnosis, demonstrating characteristic T1 hyperintensity in the right basal ganglia. Implementation of gradual glycemic control over 48 hours led to significant improvement of her symptoms. This case emphasizes the importance of considering CHBG in the differential diagnosis of movement disorders in patients with uncontrolled diabetes. Early recognition and prompt glycemic management can lead to complete resolution of symptoms, highlighting the crucial role of maintaining proper blood sugar control in diabetic patients.
format Article
id doaj-art-82d517d2d5874fcfabb297812f561e90
institution DOAJ
issn 1179-5476
language English
publishDate 2025-05-01
publisher SAGE Publishing
record_format Article
series Clinical Medicine Insights: Case Reports
spelling doaj-art-82d517d2d5874fcfabb297812f561e902025-08-20T03:12:26ZengSAGE PublishingClinical Medicine Insights: Case Reports1179-54762025-05-011810.1177/11795476251345877Reversal of Chorea Hyperglycemia Basal Ganglia Syndrome With Glycemic Control: A Case ReportSumanth Gundraju0Jaideep Menda1Tarun Kumar Suvvari2Anupama Kumudavalli Pindi3Prudhvi Kumar Davala4Tejinder Singh5Vimal Thomas6Squad Medicine and Research (SMR), Amadalavalasa, Andhra Pradesh, IndiaDepartment of Medicine, All India Institute of Medical Sciences (AIIMS), New Delhi, IndiaSquad Medicine and Research (SMR), Amadalavalasa, Andhra Pradesh, IndiaSquad Medicine and Research (SMR), Amadalavalasa, Andhra Pradesh, IndiaSquad Medicine and Research (SMR), Amadalavalasa, Andhra Pradesh, IndiaOdessa National Medical University, Odessa, UkraineTbilisi State Medical University, Tbilisi, GeorgiaChorea Hyperglycemia Basal Ganglia Syndrome (CHBG) is an uncommon neurological complication arising in diabetic patients with severe, non-ketotic hyperglycemia. This case report describes a 50-year-old woman presenting with new-onset, choreiform movements in her extremities. Initial workup revealed uncontrolled diabetes (plasma glucose 410 mg/dl, HbA1c 11.2%) with negative serum ketones. Brain MRI findings supported the diagnosis, demonstrating characteristic T1 hyperintensity in the right basal ganglia. Implementation of gradual glycemic control over 48 hours led to significant improvement of her symptoms. This case emphasizes the importance of considering CHBG in the differential diagnosis of movement disorders in patients with uncontrolled diabetes. Early recognition and prompt glycemic management can lead to complete resolution of symptoms, highlighting the crucial role of maintaining proper blood sugar control in diabetic patients.https://doi.org/10.1177/11795476251345877
spellingShingle Sumanth Gundraju
Jaideep Menda
Tarun Kumar Suvvari
Anupama Kumudavalli Pindi
Prudhvi Kumar Davala
Tejinder Singh
Vimal Thomas
Reversal of Chorea Hyperglycemia Basal Ganglia Syndrome With Glycemic Control: A Case Report
Clinical Medicine Insights: Case Reports
title Reversal of Chorea Hyperglycemia Basal Ganglia Syndrome With Glycemic Control: A Case Report
title_full Reversal of Chorea Hyperglycemia Basal Ganglia Syndrome With Glycemic Control: A Case Report
title_fullStr Reversal of Chorea Hyperglycemia Basal Ganglia Syndrome With Glycemic Control: A Case Report
title_full_unstemmed Reversal of Chorea Hyperglycemia Basal Ganglia Syndrome With Glycemic Control: A Case Report
title_short Reversal of Chorea Hyperglycemia Basal Ganglia Syndrome With Glycemic Control: A Case Report
title_sort reversal of chorea hyperglycemia basal ganglia syndrome with glycemic control a case report
url https://doi.org/10.1177/11795476251345877
work_keys_str_mv AT sumanthgundraju reversalofchoreahyperglycemiabasalgangliasyndromewithglycemiccontrolacasereport
AT jaideepmenda reversalofchoreahyperglycemiabasalgangliasyndromewithglycemiccontrolacasereport
AT tarunkumarsuvvari reversalofchoreahyperglycemiabasalgangliasyndromewithglycemiccontrolacasereport
AT anupamakumudavallipindi reversalofchoreahyperglycemiabasalgangliasyndromewithglycemiccontrolacasereport
AT prudhvikumardavala reversalofchoreahyperglycemiabasalgangliasyndromewithglycemiccontrolacasereport
AT tejindersingh reversalofchoreahyperglycemiabasalgangliasyndromewithglycemiccontrolacasereport
AT vimalthomas reversalofchoreahyperglycemiabasalgangliasyndromewithglycemiccontrolacasereport