Outcomes of Endovascular Therapy for Salvage of Hemodialysis Arteriovenous Fistulae

Introduction Arteriovenous fistulae (AVF) for hemodialysis (HD) are prone to development of multiple complications, which can lead to nonfunctioning of the fistula. We report outcomes of endovascular management for dysfunctional HD AVF. Materials and Methods In this prospective study, pat...

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Main Authors: Nishtha Yadav, Shivanand Gamanagatti, Raju Sharma, Sanjay Kumar Aggarwal, V. K. Bansal, Devasenathipathy Kandasamy, V. Seenu
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2021-06-01
Series:Journal of Clinical Interventional Radiology ISVIR
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Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1728983
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author Nishtha Yadav
Shivanand Gamanagatti
Raju Sharma
Sanjay Kumar Aggarwal
V. K. Bansal
Devasenathipathy Kandasamy
V. Seenu
author_facet Nishtha Yadav
Shivanand Gamanagatti
Raju Sharma
Sanjay Kumar Aggarwal
V. K. Bansal
Devasenathipathy Kandasamy
V. Seenu
author_sort Nishtha Yadav
collection DOAJ
description Introduction Arteriovenous fistulae (AVF) for hemodialysis (HD) are prone to development of multiple complications, which can lead to nonfunctioning of the fistula. We report outcomes of endovascular management for dysfunctional HD AVF. Materials and Methods In this prospective study, patients (43 men, 28 women, mean age 47.4 years) with clinical signs and symptoms of dysfunctional HD AVF and referred to interventional radiology for endovascular management were included. The most common clinical presentation included low flows during hemodialysis (n = 20), absent flow (n = 37), and failure of fistula maturation (n = 14). Patients with central venous obstruction who presented with limb swelling were excluded from this study. Patients underwent venography, venoplasty and thrombectomy, as appropriate, to salvage the fistula. The study outcomes were technical success, hemodynamic success, and clinical success of endovascular therapies in salvaging the fistulae. Results The technical, hemodynamic and clinical success rates of endovascular therapy for low-flow symptoms were 95%, 70% and 95%, respectively. Among patients who presented with absent flow, endovascular therapy had 81% technical success, 78.3% hemodynamic success, and 81% clinical success. Endovascular therapy was associated with 64.2% technical success, 57.1% hemodynamic success, and 64.2% clinical success in patients presenting with failed maturation of the fistula. The overall clinical success rate was 58/71 (81.7%) and failure rate was 13/71 (18.3%). The overall complication rate of endovascular therapy was 8.4% and the complications included vein rupture in 5 (7%) and balloon rupture in 1 (1.4%). Conclusion Endovascular therapy for salvage of nonfunctioning hemodialysis AVF is associated with a high-clinical success rate (81.7%) and low-complication rate.
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spelling doaj-art-82ccec42fd7849ad9680a6baff8e778b2025-08-20T02:08:46ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Clinical Interventional Radiology ISVIR2456-48692021-06-01050314214910.1055/s-0041-1728983Outcomes of Endovascular Therapy for Salvage of Hemodialysis Arteriovenous FistulaeNishtha Yadav0Shivanand Gamanagatti1Raju Sharma2Sanjay Kumar Aggarwal3V. K. Bansal4Devasenathipathy Kandasamy5V. Seenu6Department of Radiology, Super Speciality Hospital, NSCB Medical College, Jabalpur, Madhya Pradesh, IndiaDepartment of Radiology, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Radiology, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Nephrology, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Surgery, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Radiology, All India Institute of Medical Sciences, New Delhi, IndiaDepartment of Surgery, All India Institute of Medical Sciences, New Delhi, IndiaIntroduction Arteriovenous fistulae (AVF) for hemodialysis (HD) are prone to development of multiple complications, which can lead to nonfunctioning of the fistula. We report outcomes of endovascular management for dysfunctional HD AVF. Materials and Methods In this prospective study, patients (43 men, 28 women, mean age 47.4 years) with clinical signs and symptoms of dysfunctional HD AVF and referred to interventional radiology for endovascular management were included. The most common clinical presentation included low flows during hemodialysis (n = 20), absent flow (n = 37), and failure of fistula maturation (n = 14). Patients with central venous obstruction who presented with limb swelling were excluded from this study. Patients underwent venography, venoplasty and thrombectomy, as appropriate, to salvage the fistula. The study outcomes were technical success, hemodynamic success, and clinical success of endovascular therapies in salvaging the fistulae. Results The technical, hemodynamic and clinical success rates of endovascular therapy for low-flow symptoms were 95%, 70% and 95%, respectively. Among patients who presented with absent flow, endovascular therapy had 81% technical success, 78.3% hemodynamic success, and 81% clinical success. Endovascular therapy was associated with 64.2% technical success, 57.1% hemodynamic success, and 64.2% clinical success in patients presenting with failed maturation of the fistula. The overall clinical success rate was 58/71 (81.7%) and failure rate was 13/71 (18.3%). The overall complication rate of endovascular therapy was 8.4% and the complications included vein rupture in 5 (7%) and balloon rupture in 1 (1.4%). Conclusion Endovascular therapy for salvage of nonfunctioning hemodialysis AVF is associated with a high-clinical success rate (81.7%) and low-complication rate.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1728983arteriovenous fistulahemodialysis accessinterventional radiologyballoon dilatationvenoplasty
spellingShingle Nishtha Yadav
Shivanand Gamanagatti
Raju Sharma
Sanjay Kumar Aggarwal
V. K. Bansal
Devasenathipathy Kandasamy
V. Seenu
Outcomes of Endovascular Therapy for Salvage of Hemodialysis Arteriovenous Fistulae
Journal of Clinical Interventional Radiology ISVIR
arteriovenous fistula
hemodialysis access
interventional radiology
balloon dilatation
venoplasty
title Outcomes of Endovascular Therapy for Salvage of Hemodialysis Arteriovenous Fistulae
title_full Outcomes of Endovascular Therapy for Salvage of Hemodialysis Arteriovenous Fistulae
title_fullStr Outcomes of Endovascular Therapy for Salvage of Hemodialysis Arteriovenous Fistulae
title_full_unstemmed Outcomes of Endovascular Therapy for Salvage of Hemodialysis Arteriovenous Fistulae
title_short Outcomes of Endovascular Therapy for Salvage of Hemodialysis Arteriovenous Fistulae
title_sort outcomes of endovascular therapy for salvage of hemodialysis arteriovenous fistulae
topic arteriovenous fistula
hemodialysis access
interventional radiology
balloon dilatation
venoplasty
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0041-1728983
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