Comprehensive Complication Index Predicts Cancer-Specific Survival of Patients with Postoperative Complications after Curative Resection of Gastric Cancer
Objective. To investigate the prognostic impact of postoperative complications for patients with gastric cancer. Methods. Postoperative complications of patients undergoing radical gastrectomy for gastric cancer were reviewed. The severity of complications was graded by the CCI and C-D classificatio...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Gastroenterology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2018/4396018 |
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| author | Ru-Hong Tu Jian-Xian Lin Ping Li Jian-Wei Xie Jia-Bin Wang Jun Lu Qi-Yue Chen Long-long Cao Mi Lin Chao-Hui Zheng Chang-Ming Huang |
| author_facet | Ru-Hong Tu Jian-Xian Lin Ping Li Jian-Wei Xie Jia-Bin Wang Jun Lu Qi-Yue Chen Long-long Cao Mi Lin Chao-Hui Zheng Chang-Ming Huang |
| author_sort | Ru-Hong Tu |
| collection | DOAJ |
| description | Objective. To investigate the prognostic impact of postoperative complications for patients with gastric cancer. Methods. Postoperative complications of patients undergoing radical gastrectomy for gastric cancer were reviewed. The severity of complications was graded by the CCI and C-D classification. Results. A total of 5327 patients were included in the study. Complications were observed in 767 patients. When the C-D classification system was applied, for patients with grade I–II complications, the length of stay (LOS) of those with high CCI (CCI ≥ 26.2) was significantly longer than that of patients with low CCI (CCI < 26.2) (p<0.001). The 5-year cancer-specific survival rate of patients with complications (52%) was lower than that of patients without complications (61%) (p<0.001). Analysis of the factors associated with prognosis in patients with gastric cancer revealed that complications were independent risk factors for specific survival. When CCI was used to classify complication severity, the 5-year cancer-specific survival rate of the high-CCI group was 46.3%, which was lower than that of the low-CCI group (54.9%, p=0.009). Conclusion. Complication after radical gastrectomy is an independent prognostic factor, and the complication severity as graded by CCI reflects the difference of cancer-specific survival in gastric cancer patients with postoperative complications. |
| format | Article |
| id | doaj-art-82c9e625953548618f74139bed491207 |
| institution | Kabale University |
| issn | 1687-6121 1687-630X |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Gastroenterology Research and Practice |
| spelling | doaj-art-82c9e625953548618f74139bed4912072025-02-03T00:59:15ZengWileyGastroenterology Research and Practice1687-61211687-630X2018-01-01201810.1155/2018/43960184396018Comprehensive Complication Index Predicts Cancer-Specific Survival of Patients with Postoperative Complications after Curative Resection of Gastric CancerRu-Hong Tu0Jian-Xian Lin1Ping Li2Jian-Wei Xie3Jia-Bin Wang4Jun Lu5Qi-Yue Chen6Long-long Cao7Mi Lin8Chao-Hui Zheng9Chang-Ming Huang10Department of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaDepartment of Gastric Surgery, Fujian Medical University Union Hospital, Fuzhou, ChinaObjective. To investigate the prognostic impact of postoperative complications for patients with gastric cancer. Methods. Postoperative complications of patients undergoing radical gastrectomy for gastric cancer were reviewed. The severity of complications was graded by the CCI and C-D classification. Results. A total of 5327 patients were included in the study. Complications were observed in 767 patients. When the C-D classification system was applied, for patients with grade I–II complications, the length of stay (LOS) of those with high CCI (CCI ≥ 26.2) was significantly longer than that of patients with low CCI (CCI < 26.2) (p<0.001). The 5-year cancer-specific survival rate of patients with complications (52%) was lower than that of patients without complications (61%) (p<0.001). Analysis of the factors associated with prognosis in patients with gastric cancer revealed that complications were independent risk factors for specific survival. When CCI was used to classify complication severity, the 5-year cancer-specific survival rate of the high-CCI group was 46.3%, which was lower than that of the low-CCI group (54.9%, p=0.009). Conclusion. Complication after radical gastrectomy is an independent prognostic factor, and the complication severity as graded by CCI reflects the difference of cancer-specific survival in gastric cancer patients with postoperative complications.http://dx.doi.org/10.1155/2018/4396018 |
| spellingShingle | Ru-Hong Tu Jian-Xian Lin Ping Li Jian-Wei Xie Jia-Bin Wang Jun Lu Qi-Yue Chen Long-long Cao Mi Lin Chao-Hui Zheng Chang-Ming Huang Comprehensive Complication Index Predicts Cancer-Specific Survival of Patients with Postoperative Complications after Curative Resection of Gastric Cancer Gastroenterology Research and Practice |
| title | Comprehensive Complication Index Predicts Cancer-Specific Survival of Patients with Postoperative Complications after Curative Resection of Gastric Cancer |
| title_full | Comprehensive Complication Index Predicts Cancer-Specific Survival of Patients with Postoperative Complications after Curative Resection of Gastric Cancer |
| title_fullStr | Comprehensive Complication Index Predicts Cancer-Specific Survival of Patients with Postoperative Complications after Curative Resection of Gastric Cancer |
| title_full_unstemmed | Comprehensive Complication Index Predicts Cancer-Specific Survival of Patients with Postoperative Complications after Curative Resection of Gastric Cancer |
| title_short | Comprehensive Complication Index Predicts Cancer-Specific Survival of Patients with Postoperative Complications after Curative Resection of Gastric Cancer |
| title_sort | comprehensive complication index predicts cancer specific survival of patients with postoperative complications after curative resection of gastric cancer |
| url | http://dx.doi.org/10.1155/2018/4396018 |
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