Effects of different flow rates in HFNC oxygen therapy on the success rate of weaning, blood gas and prognosis in elderly patients with severe pneumonia and difficulty in weaning
[Objective] To analyze the effects of different flow rates in high-flow nasal cannula oxygen therapy on the success rate of weaning, blood gas and prognosis in elderly patients with severe pneumonia and difficulty in weaning. [Methods] A retrospective analysis was conducted on the data of 81 elderly...
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Editorial Office of International Journal of Geriatrics
2025-07-01
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| Series: | Guoji laonian yixue zazhi |
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| Online Access: | http://gwll.publish.founderss.cn/thesisDetails#10.3969/j.issn.1674-7593.2025.04.011&lang=en |
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| author | Tang Gaorou Lu Guoyu |
| author_facet | Tang Gaorou Lu Guoyu |
| author_sort | Tang Gaorou |
| collection | DOAJ |
| description | [Objective] To analyze the effects of different flow rates in high-flow nasal cannula oxygen therapy on the success rate of weaning, blood gas and prognosis in elderly patients with severe pneumonia and difficulty in weaning. [Methods] A retrospective analysis was conducted on the data of 81 elderly patients with severe pneumonia and difficulty in weaning who were admitted to the second Affiliated Hospital of Bengbu Medical University from November 2022 to October 2024. All patients enrolled were given sequential high-flow nasal cannula after extubation in the ICU. According to the flow rate in oxygen therapy, they were divided into group A (41 cases, 40L/min) and group B (40 cases, 50L/min). The effect of weaning, patient comfort level, blood gas indicators, and the prognosis were compared between the two groups. [Results] The rate of second intubation within 7 days and success rate of weaning showed no statistically significant difference between the two groups (P>0.05). The scores for dry mouth and nasal cavity, and sore throat in group A were significantly lower than those in group B (P<0.05). The arterial partial pressure of oxygen, arterial partial pressure of carbon dioxide and pH showed no statistically significant difference between the two groups (P>0.05). The incidence rates of adverse reactions in the two groups during oxygen therapy were close (P>0.05). The length of ICU stay, length of hospital stay and the proportion of patients with poor prognosis during 28-day follow-up showed no statistically significant difference between the two groups (P>0.05). [Conclusion] High-flow nasal cannula oxygen therapy with a flow rate of 40L/min can significantly increase comfort level of elderly patients with severe pneumonia, without significant influence on the success rate of weaning, blood gas indexes and short-term prognosis. |
| format | Article |
| id | doaj-art-82c324f94d434a4cb4891b591b0fda99 |
| institution | DOAJ |
| issn | 1674-7593 |
| language | zho |
| publishDate | 2025-07-01 |
| publisher | Editorial Office of International Journal of Geriatrics |
| record_format | Article |
| series | Guoji laonian yixue zazhi |
| spelling | doaj-art-82c324f94d434a4cb4891b591b0fda992025-08-20T02:41:39ZzhoEditorial Office of International Journal of GeriatricsGuoji laonian yixue zazhi1674-75932025-07-0146444044410.3969/j.issn.1674-7593.2025.04.011Effects of different flow rates in HFNC oxygen therapy on the success rate of weaning, blood gas and prognosis in elderly patients with severe pneumonia and difficulty in weaningTang Gaorou0Lu Guoyu1Department of Emergency Medicine, the Second Affiliated Hospital of Bengbu Medical University, Bengbu 233040Department of Emergency Medicine, the First Affiliated Hospital of Bengbu Medical University, Bengbu 233004[Objective] To analyze the effects of different flow rates in high-flow nasal cannula oxygen therapy on the success rate of weaning, blood gas and prognosis in elderly patients with severe pneumonia and difficulty in weaning. [Methods] A retrospective analysis was conducted on the data of 81 elderly patients with severe pneumonia and difficulty in weaning who were admitted to the second Affiliated Hospital of Bengbu Medical University from November 2022 to October 2024. All patients enrolled were given sequential high-flow nasal cannula after extubation in the ICU. According to the flow rate in oxygen therapy, they were divided into group A (41 cases, 40L/min) and group B (40 cases, 50L/min). The effect of weaning, patient comfort level, blood gas indicators, and the prognosis were compared between the two groups. [Results] The rate of second intubation within 7 days and success rate of weaning showed no statistically significant difference between the two groups (P>0.05). The scores for dry mouth and nasal cavity, and sore throat in group A were significantly lower than those in group B (P<0.05). The arterial partial pressure of oxygen, arterial partial pressure of carbon dioxide and pH showed no statistically significant difference between the two groups (P>0.05). The incidence rates of adverse reactions in the two groups during oxygen therapy were close (P>0.05). The length of ICU stay, length of hospital stay and the proportion of patients with poor prognosis during 28-day follow-up showed no statistically significant difference between the two groups (P>0.05). [Conclusion] High-flow nasal cannula oxygen therapy with a flow rate of 40L/min can significantly increase comfort level of elderly patients with severe pneumonia, without significant influence on the success rate of weaning, blood gas indexes and short-term prognosis.http://gwll.publish.founderss.cn/thesisDetails#10.3969/j.issn.1674-7593.2025.04.011&lang=ensevere pneumoniahigh-flow nasal cannulaoxygen therapy flow ratesuccess rate of weaningblood gas |
| spellingShingle | Tang Gaorou Lu Guoyu Effects of different flow rates in HFNC oxygen therapy on the success rate of weaning, blood gas and prognosis in elderly patients with severe pneumonia and difficulty in weaning Guoji laonian yixue zazhi severe pneumonia high-flow nasal cannula oxygen therapy flow rate success rate of weaning blood gas |
| title | Effects of different flow rates in HFNC oxygen therapy on the success rate of weaning, blood gas and prognosis in elderly patients with severe pneumonia and difficulty in weaning |
| title_full | Effects of different flow rates in HFNC oxygen therapy on the success rate of weaning, blood gas and prognosis in elderly patients with severe pneumonia and difficulty in weaning |
| title_fullStr | Effects of different flow rates in HFNC oxygen therapy on the success rate of weaning, blood gas and prognosis in elderly patients with severe pneumonia and difficulty in weaning |
| title_full_unstemmed | Effects of different flow rates in HFNC oxygen therapy on the success rate of weaning, blood gas and prognosis in elderly patients with severe pneumonia and difficulty in weaning |
| title_short | Effects of different flow rates in HFNC oxygen therapy on the success rate of weaning, blood gas and prognosis in elderly patients with severe pneumonia and difficulty in weaning |
| title_sort | effects of different flow rates in hfnc oxygen therapy on the success rate of weaning blood gas and prognosis in elderly patients with severe pneumonia and difficulty in weaning |
| topic | severe pneumonia high-flow nasal cannula oxygen therapy flow rate success rate of weaning blood gas |
| url | http://gwll.publish.founderss.cn/thesisDetails#10.3969/j.issn.1674-7593.2025.04.011&lang=en |
| work_keys_str_mv | AT tanggaorou effectsofdifferentflowratesinhfncoxygentherapyonthesuccessrateofweaningbloodgasandprognosisinelderlypatientswithseverepneumoniaanddifficultyinweaning AT luguoyu effectsofdifferentflowratesinhfncoxygentherapyonthesuccessrateofweaningbloodgasandprognosisinelderlypatientswithseverepneumoniaanddifficultyinweaning |